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    gpat4 glycerol-3-phosphate acyltransferase 4 [ Danio rerio (zebrafish) ]

    Gene ID: 678522, updated on 23-Jun-2024

    Summary

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    Official Symbol
    gpat4provided by ZNC
    Official Full Name
    glycerol-3-phosphate acyltransferase 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060421-5102
    See related
    Ensembl:ENSDARG00000019897 AllianceGenome:ZFIN:ZDB-GENE-060421-5102
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    agpat6; wu:fi89e03; zgc:136875
    Summary
    Predicted to enable acyltransferase activity. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Is expressed in female organism. Orthologous to human GPAT4 (glycerol-3-phosphate acyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See gpat4 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (41362390..41399988, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (41440510..41478108, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene RAB11 family interacting protein 1 (class I) b Neighboring gene BRF2 RNA polymerase III transcription initiation factor subunit Neighboring gene calcium binding protein 1b Neighboring gene gamma-glutamyltransferase 5b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A novel system to quantify intestinal lipid digestion and transport. Sæle Ø, et al. Biochim Biophys Acta Mol Cell Biol Lipids, 2018 Sep. PMID 29778665, Free PMC Article
    2. Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production. Newman M, et al. Mol Brain, 2019 May 3. PMID 31053140, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC136875, MGC152671

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 1-acylglycerol-3-phosphate O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables O-acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glycerol-3-phosphate acyltransferase 4
    Names
    1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)
    NP_001035339.2
    XP_021334870.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001040249.2 → NP_001035339.2  glycerol-3-phosphate acyltransferase 4

      See identical proteins and their annotated locations for NP_001035339.2

      Status: PROVISIONAL

      Source sequence(s)
      BC124075
      UniProtKB/TrEMBL
      A0A0M3HEP0, A0A8N7XJL3, F6P543, Q08CV3
      Related
      ENSDARP00000022427.6, ENSDART00000009838.7
      Conserved Domains (1) summary
      cd07991
      Location:213 → 422
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      41362390..41399988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479195.1 → XP_021334870.1  glycerol-3-phosphate acyltransferase 4 isoform X1

      UniProtKB/TrEMBL
      A0A0M3HEP0, A0A8N7XJL3, F6P543, Q08CV3
      Related
      ENSDARP00000140808.2, ENSDART00000158038.2
      Conserved Domains (1) summary
      cd07991
      Location:213 → 422
      LPLAT_LPCAT1-like; Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
    Nucleotide Protein Strain
    Heading Accession and Version

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