mllt3 MLLT3 super elongation complex subunit [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mllt3provided by ZNC
Official Full Name: MLLT3 super elongation complex subunitprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-356
See related: Ensembl:ENSDARG00000006754 AllianceGenome:ZFIN:ZDB-GENE-050417-356
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc39c11; wu:fc39c11; zgc:110210
Summary: Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including immature eye; neural rod; segmental plate; sensory system; and tail bud. Orthologous to human MLLT3 (MLLT3 super elongation complex subunit). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (18778210..18881358, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (18527288..18629091, complement)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis.
Title: Leukemia-associated transcription factor mllt3 is important for primitive erythroid development in zebrafish embryogenesis.

Submit: New GeneRIF Correction

General gene information

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Markers

G39248 (e-PCR)
- UniSTS:60939

fc39c11.x1 (e-PCR)
- UniSTS:193754

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables lysine-acetylated histone binding	IBA Inferred from Biological aspect of Ancestor more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in positive regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription elongation factor complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein AF-9

Names: myeloid/lymphoid or mixed lineage-leukemia translocation to 3 homolog; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017819.1 → NP_001017819.1 protein AF-9

See identical proteins and their annotated locations for NP_001017819.1

Status: PROVISIONAL

Source sequence(s)

BC092798

UniProtKB/TrEMBL

Q568M5

Related

ENSDARP00000004230.6, ENSDART00000021502.9

Conserved Domains (1) summary

pfam03366
Location:1 → 77

YEATS; YEATS family

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

18778210..18881358 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021477527.1 → XP_021333202.1 protein AF-9 isoform X2

UniProtKB/TrEMBL

A0A8M9PNX3

Conserved Domains (1) summary

pfam03366
Location:1 → 77

YEATS; YEATS family
XM_009303057.3 → XP_009301332.1 protein AF-9 isoform X1

UniProtKB/TrEMBL

A0A8M3BAV5

Conserved Domains (1) summary

pfam03366
Location:29 → 109

YEATS; YEATS family
XM_021477528.1 → XP_021333203.1 protein AF-9 isoform X3

UniProtKB/TrEMBL

A0A8M9Q1L0