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    slc38a7 solute carrier family 38 member 7 [ Danio rerio (zebrafish) ]

    Gene ID: 445254, updated on 11-Apr-2024

    Summary

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    Official Symbol
    slc38a7provided by ZNC
    Official Full Name
    solute carrier family 38 member 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040801-266
    See related
    Ensembl:ENSDARG00000012002 AllianceGenome:ZFIN:ZDB-GENE-040801-266
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb389; fb71c10; fi23b07; sb:cb389; wu:fb71c10; wu:fi23b07; zgc:100802
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to act upstream of or within amino acid transport and sodium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in mesoderm; musculature system; myotome; somite; and yolk syncytial layer. Orthologous to human SLC38A7 (solute carrier family 38 member 7). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See slc38a7 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (51795702..51814891)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (51520627..51539819)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein 15 Neighboring gene glutamic-oxaloacetic transaminase 2b, mitochondrial Neighboring gene si:ch211-122f10.4 Neighboring gene uncharacterized LOC103911422

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Thyme SB, et al. Cell, 2019 Apr 4. PMID 30929901, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables L-asparagine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-asparagine:sodium symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables L-glutamine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-glutamine:sodium symporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in asparagine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in glutamine transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lysosomal membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sodium-coupled neutral amino acid transporter 7; putative sodium-coupled neutral amino acid transporter 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003648.1 → NP_001003648.1  sodium-coupled neutral amino acid transporter 7

      See identical proteins and their annotated locations for NP_001003648.1

      Status: PROVISIONAL

      Source sequence(s)
      BC077100
      UniProtKB/Swiss-Prot
      Q498Q4, Q6DEL1
      Related
      ENSDARP00000026295.6, ENSDART00000026571.7
      Conserved Domains (2) summary
      COG0814
      Location:47 → 446
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:47 → 454
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      51795702..51814891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166513.4 → XP_005166570.1  putative sodium-coupled neutral amino acid transporter 7 isoform X1

      See identical proteins and their annotated locations for XP_005166570.1

      UniProtKB/TrEMBL
      A0A8M2BE36, F1QUV9
      Related
      ENSDARP00000068329.5, ENSDART00000073839.8
      Conserved Domains (2) summary
      COG0814
      Location:47 → 446
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:47 → 454
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_009303440.3 → XP_009301715.1  putative sodium-coupled neutral amino acid transporter 7 isoform X1

      See identical proteins and their annotated locations for XP_009301715.1

      UniProtKB/TrEMBL
      A0A8M2BE36, F1QUV9
      Related
      ENSDARP00000143162.1, ENSDART00000174201.2
      Conserved Domains (2) summary
      COG0814
      Location:47 → 446
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:47 → 454
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6DEL1.1 GenPept UniProtKB/Swiss-Prot:Q6DEL1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.