tnni2a.3 troponin I type 2a (skeletal, fast), tandem duplicate 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tnni2a.3provided by ZNC
Official Full Name: troponin I type 2a (skeletal, fast), tandem duplicate 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-80
See related: Ensembl:ENSDARG00000013752 AllianceGenome:ZFIN:ZDB-GENE-040718-80
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92053
Summary: Predicted to be involved in cardiac muscle contraction and skeletal muscle contraction. Predicted to be part of troponin complex. Is expressed in muscle; musculature system; myotome; and pectoral fin musculature. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita; distal arthrogryposis type 2B1; and intrinsic cardiomyopathy (multiple). Orthologous to several human genes including TNNI2 (troponin I2, fast skeletal type). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 25

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (31264862..31275790)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (30687386..30698314)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cardiac muscle contraction	IBA Inferred from Biological aspect of Ancestor more info
involved_in skeletal muscle contraction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of troponin complex	IBA Inferred from Biological aspect of Ancestor more info
part_of troponin complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: troponin I type 2a (skeletal, fast), tandem duplicate 3

Names: tropI-1c; troponin I, skeletal, fast 2a, tandem duplicate 3; troponin I, skeletal, fast 2a.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.