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    TRIM52-AS1 TRIM52 antisense RNA 1 (head to head) [ Homo sapiens (human) ]

    Gene ID: 100507602, updated on 10-Oct-2023

    Summary

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    Official Symbol
    TRIM52-AS1provided by HGNC
    Official Full Name
    TRIM52 antisense RNA 1 (head to head)provided by HGNC
    Primary source
    HGNC:HGNC:49006
    See related
    Ensembl:ENSG00000248275 MIM:619266; AllianceGenome:HGNC:49006
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in fat (RPKM 3.9), thyroid (RPKM 3.5) and 25 other tissues See more
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    Genomic context

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    See TRIM52-AS1 in Genome Data Viewer
    Location:
    5q35.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (181261212..181272307)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (181821165..181832260)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (180688213..180699308)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23790 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23791 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23792 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:180672476-180673404 Neighboring gene receptor for activated C kinase 1 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:180673405-180674331 Neighboring gene uncharacterized LOC101928649 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:180674332-180675259 Neighboring gene small nucleolar RNA, C/D box 95 Neighboring gene tripartite motif containing 52 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23794 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23795 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16798 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16799 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:180691856-180692474 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:180692475-180693092 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:180694171-180694740 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:180694741-180695310 Neighboring gene H3K27ac hESC enhancer GRCh37_chr5:180707611-180708313 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:180711037-180711557 Neighboring gene RNA, U6 small nuclear 705, pseudogene Neighboring gene uncharacterized LOC100132062 Neighboring gene capicua transcriptional repressor pseudogene 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Downregulation of long non-coding RNA TRIM52-AS1 functions as a tumor suppressor in renal cell carcinoma. Liu Z, et al. Mol Med Rep, 2016 Apr. PMID 26934858
    2. Long Noncoding RNA TRIM52-AS1 Sponges miR-514a-5p to Facilitate Hepatocellular Carcinoma Progression Through Increasing MRPS18A. Zhou C, et al. Cancer Biother Radiopharm, 2021 Mar. PMID 32391716
    3. miR-96-5p regulates cervical cancer cell resistance to cisplatin by inhibiting lncRNA TRIM52-AS1 and promoting IGF2BP2. Wu EY, et al. Kaohsiung J Med Sci, 2022 Dec. PMID 36354205
    4. Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression. Zhao F, et al. Hum Cell, 2022 Jul. PMID 35676608
    5. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. miR-96-5p regulates cervical cancer cell resistance to cisplatin by inhibiting lncRNA TRIM52-AS1 and promoting IGF2BP2.
      Title: miR-96-5p regulates cervical cancer cell resistance to cisplatin by inhibiting lncRNA TRIM52-AS1 and promoting IGF2BP2.
    2. Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression.
      Title: Long non-coding RNA TRIM52-AS1 sponges microRNA-577 to facilitate diffuse large B cell lymphoma progression via increasing TRIM52 expression.
    3. Long Noncoding RNA TRIM52-AS1 Sponges miR-514a-5p to Facilitate Hepatocellular Carcinoma Progression Through Increasing MRPS18A.
      Title: Long Noncoding RNA TRIM52-AS1 Sponges miR-514a-5p to Facilitate Hepatocellular Carcinoma Progression Through Increasing MRPS18A.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • CTC-338M12.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_102759.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript.
      Source sequence(s)
      AC008443, BQ778070, CK905273
      Related
      ENST00000657194.2

    2. NR_102760.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal segment, compared to variant 1.
      Source sequence(s)
      AC008443, BM014221, BQ778070
      Related
      ENST00000509252.2

    3. NR_102761.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an internal segment, compared to variant 1.
      Source sequence(s)
      AC008443, BQ778070, HY116666
      Related
      ENST00000433265.5

    4. NR_102762.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has an alternate and shorter 3' sequence, compared to variant 1.
      Source sequence(s)
      BC016291, BQ778070, HY123799
      Related
      ENST00000507434.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      181261212..181272307
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      181821165..181832260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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