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    PALS1 protein associated with LIN7 1, MAGUK p55 family member [ Bos taurus (cattle) ]

    Gene ID: 528109, updated on 6-Jun-2024

    Summary

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    Official Symbol
    PALS1provided by VGNC
    Official Full Name
    protein associated with LIN7 1, MAGUK p55 family memberprovided by VGNC
    Primary source
    VGNC:VGNC:31584
    See related
    BGD:BT23582; Ensembl:ENSBTAG00000011767
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    MPP5
    Orthologs
    human mouse all
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    Genomic context

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    See PALS1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (79157760..79238619)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene gephyrin Neighboring gene golgi associated RAB2 interactor family member 2 Neighboring gene ATPase H+ transporting V1 subunit D Neighboring gene eukaryotic translation initiation factor 2 subunit alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in establishment or maintenance of polarity of embryonic epithelium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in generation of neurons IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in morphogenesis of an epithelial sheet IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein PALS1
    Names
    membrane palmitoylated protein 5
    membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
    protein associated with LIN7 1, MAGUK family member

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205951.1 → NP_001192880.1  protein PALS1

      See identical proteins and their annotated locations for NP_001192880.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000010
      UniProtKB/TrEMBL
      A0A3Q1LY00, E1BIQ8
      Related
      ENSBTAP00000062138.1, ENSBTAT00000081434.2
      Conserved Domains (5) summary
      smart00569
      Location:189 → 237
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12036
      Location:349 → 411
      SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
      smart00072
      Location:491 → 661
      GuKc; Guanylate kinase homologues
      cd00992
      Location:254 → 333
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam09060
      Location:123 → 170
      L27_N; L27_N

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      79157760..79238619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015473234.3 → XP_015328720.1  protein PALS1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LY00, E1BIQ8
      Conserved Domains (5) summary
      smart00569
      Location:189 → 237
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12036
      Location:349 → 411
      SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
      smart00072
      Location:491 → 661
      GuKc; Guanylate kinase homologues
      cd00992
      Location:254 → 333
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam09060
      Location:123 → 170
      L27_N; L27_N

    2. XM_005211983.5 → XP_005212040.1  protein PALS1 isoform X2

      See identical proteins and their annotated locations for XP_005212040.1

      UniProtKB/TrEMBL
      E1BIQ8
      Conserved Domains (5) summary
      smart00569
      Location:155 → 203
      L27; domain in receptor targeting proteins Lin-2 and Lin-7
      cd12036
      Location:315 → 377
      SH3_MPP5; Src Homology 3 domain of Membrane Protein, Palmitoylated 5 (or MAGUK p55 subfamily member 5)
      smart00072
      Location:457 → 627
      GuKc; Guanylate kinase homologues
      cd00992
      Location:220 → 299
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam09060
      Location:89 → 136
      L27_N; L27_N
    Nucleotide Protein Strain
    Heading Accession and Version

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