PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta [Bos taurus (cattle)] - Gene

Summary

Official Symbol: PRKAR2Bprovided by VGNC
Official Full Name: protein kinase cAMP-dependent type II regulatory subunit betaprovided by VGNC
Primary source: VGNC:VGNC:33326
See related: BGD:BT15095; Ensembl:ENSBTAG00000014958
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 4

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (48154294..48255027)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

angle X-ray scattering studies indicate that the RIalpha, RIIalpha, and RIIbeta homodimers differ markedly in overall shape, despite extensive sequence homology and similar molecular masses
Title: Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cAMP-dependent protein kinase regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cAMP-dependent protein kinase complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: cAMP-dependent protein kinase type II-beta regulatory subunit

Names: protein kinase, cAMP-dependent, regulatory, type II, beta

NP_777074.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_174649.2 → NP_777074.1 cAMP-dependent protein kinase type II-beta regulatory subunit

See identical proteins and their annotated locations for NP_777074.1

Status: PROVISIONAL

Source sequence(s)

J05692

UniProtKB/Swiss-Prot

P31322

UniProtKB/TrEMBL

B0JYK4

Related

ENSBTAP00000019916.5, ENSBTAT00000019916.6

Conserved Domains (3) summary

cd12104
Location:3 → 43

DD_RIIbeta_PKA; Dimerization/Docking domain of the Type II beta Regulatory subunit of cAMP-dependent protein kinase

COG0664
Location:270 → 385

Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]

cd00038
Location:276 → 396

CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...