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    POR cytochrome p450 oxidoreductase [ Bos taurus (cattle) ]

    Gene ID: 532512, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PORprovided by VGNC
    Official Full Name
    cytochrome p450 oxidoreductaseprovided by VGNC
    Primary source
    VGNC:VGNC:33169
    See related
    BGD:BT22477; Ensembl:ENSBTAG00000017082
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    P450R
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 25
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (34188053..34213377)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene rhomboid domain containing 2 Neighboring gene large ribosomal subunit protein uL6-like Neighboring gene transmembrane protein 120A Neighboring gene serine/threonine/tyrosine interacting like 1 Neighboring gene malate dehydrogenase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of nuclear receptor and target genes in liver and intestine of neonatal calves fed colostrum and vitamin A. Krüger KA, et al. J Dairy Sci, 2005 Nov. PMID 16230703
    2. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    3. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127752

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables FMN binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables NADPH-hemoprotein reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in response to hormone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADPH--cytochrome P450 reductase
    Names
    CPR
    P450 (cytochrome) oxidoreductase
    cytochrome P450 reductase
    NP_001030467.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035390.1 → NP_001030467.1  NADPH--cytochrome P450 reductase

      See identical proteins and their annotated locations for NP_001030467.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103399
      UniProtKB/TrEMBL
      A0A3S5ZP34, A5D9D3, F1MGY7
      Related
      ENSBTAP00000066469.2, ENSBTAT00000067733.2
      Conserved Domains (3) summary
      cd06204
      Location:279 → 679
      CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
      COG0369
      Location:54 → 679
      CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
      pfam00258
      Location:84 → 221
      Flavodoxin_1; Flavodoxin

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      34188053..34213377
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SYT8.3 GenPept UniProtKB/Swiss-Prot:Q3SYT8

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