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    BMPR1A bone morphogenetic protein receptor type 1A [ Bos taurus (cattle) ]

    Gene ID: 404101, updated on 6-Jun-2024

    Summary

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    Official Symbol
    BMPR1Aprovided by VGNC
    Official Full Name
    bone morphogenetic protein receptor type 1Aprovided by VGNC
    Primary source
    VGNC:VGNC:26524
    See related
    BGD:BT10028; Ensembl:ENSBTAG00000000231
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    BMPR-IA
    Orthologs
    human mouse all
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    Genomic context

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    See BMPR1A in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (41403870..41545706)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene opsin 4 Neighboring gene LIM domain binding 3 Neighboring gene multimerin 2 Neighboring gene synuclein gamma

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of bone morphogenetic protein2 (BMP2), BMP4 and BMP receptors in the bovine ovary but absence of effects of BMP2 and BMP4 during IVM on bovine oocyte nuclear maturation and subsequent embryo development. Fatehi AN, et al. Theriogenology, 2005 Feb. PMID 15629804
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transforming growth factor beta receptor activity, type I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in dorsal/ventral pattern formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bone morphogenetic protein receptor type-1A
    Names
    bone morphogenetic protein receptor IA
    bone morphogenetic protein receptor, type IA
    NP_001070268.1
    XP_005226588.1
    XP_024842344.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076800.1 → NP_001070268.1  bone morphogenetic protein receptor type-1A precursor

      See identical proteins and their annotated locations for NP_001070268.1

      Status: PROVISIONAL

      Source sequence(s)
      DQ922946
      UniProtKB/TrEMBL
      A0AAA9SHJ0, Q06AL7
      Related
      ENSBTAP00000000282.5, ENSBTAT00000000282.6
      Conserved Domains (3) summary
      smart00221
      Location:234 → 521
      STYKc; Protein kinase; unclassified specificity
      cd14220
      Location:238 → 524
      STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
      pfam01064
      Location:59 → 138
      Activin_recp; Activin types I and II receptor domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      41403870..41545706
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005226531.5 → XP_005226588.1  bone morphogenetic protein receptor type-1A isoform X1

      See identical proteins and their annotated locations for XP_005226588.1

      UniProtKB/TrEMBL
      A0AAA9SHJ0, F1MCE7
      Conserved Domains (2) summary
      cd14220
      Location:238 → 524
      STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
      pfam01064
      Location:59 → 132
      Activin_recp; Activin types I and II receptor domain

    2. XM_024986576.2 → XP_024842344.1  bone morphogenetic protein receptor type-1A isoform X2

      UniProtKB/TrEMBL
      A0AAA9SHJ0
      Conserved Domains (2) summary
      cd14220
      Location:204 → 490
      STKc_BMPR1a; Catalytic domain of the Serine/Threonine Kinase, Bone Morphogenetic Protein Type IA Receptor
      pfam01064
      Location:25 → 98
      Activin_recp; Activin types I and II receptor domain
    Nucleotide Protein Strain
    Heading Accession and Version

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