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    Ccdc91 coiled-coil domain containing 91 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 312863, updated on 2-May-2024

    Summary

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    Symbol
    Ccdc91provided by RGD
    Full Name
    coiled-coil domain containing 91provided by RGD
    Primary source
    RGD:1359502
    See related
    Ensembl:ENSRNOG00000001847 AllianceGenome:RGD:1359502
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be involved in Golgi to lysosome transport. Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in trans-Golgi network. Orthologous to human CCDC91 (coiled-coil domain containing 91). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Testes (RPKM 719.0), Muscle (RPKM 312.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ccdc91 in Genome Data Viewer
    Location:
    4q44
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (182132931..182304948)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (180402327..180574364)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (181873465..182043593)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108350879 Neighboring gene parathyroid hormone-like hormone Neighboring gene uncharacterized LOC134486874 Neighboring gene uncharacterized LOC108350795 Neighboring gene fatty acyl CoA reductase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. Mardones GA, et al. Mol Biol Cell, 2007 Sep. PMID 17596511, Free PMC Article
    2. Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. Lui WW, et al. Mol Biol Cell, 2003 Jun. PMID 12808037, Free PMC Article
    3. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in Golgi to lysosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in Golgi to lysosome transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in Golgi to lysosome transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in Golgi vesicle transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in trans-Golgi network ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 91
    Names
    GGA-binding partner
    coiled-coil domain-containing protein 91-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014061.1 → NP_001014083.1  coiled-coil domain-containing protein 91

      See identical proteins and their annotated locations for NP_001014083.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079135
      UniProtKB/Swiss-Prot
      Q6AY97
      UniProtKB/TrEMBL
      A0A8I6G845
      Related
      ENSRNOP00000002527.6, ENSRNOT00000002527.7
      Conserved Domains (1) summary
      pfam17380
      Location:130 → 442
      DUF5401; Family of unknown function (DUF5401)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      182132931..182304948
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286194.1 → XP_063142264.1  coiled-coil domain-containing protein 91 isoform X5

    2. XM_006237685.5 → XP_006237747.1  coiled-coil domain-containing protein 91 isoform X3

      UniProtKB/TrEMBL
      A0A8I6AS44, A0A8I6G845
      Related
      ENSRNOP00000097935.1
      Conserved Domains (1) summary
      PTZ00121
      Location:143 → 387
      PTZ00121; MAEBL; Provisional

    3. XM_063286192.1 → XP_063142262.1  coiled-coil domain-containing protein 91 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY97

    4. XM_063286190.1 → XP_063142260.1  coiled-coil domain-containing protein 91 isoform X1

      UniProtKB/Swiss-Prot
      Q6AY97

    5. XM_039107721.2 → XP_038963649.1  coiled-coil domain-containing protein 91 isoform X2

      UniProtKB/TrEMBL
      A0A8I6G845
      Conserved Domains (1) summary
      pfam17380
      Location:110 → 422
      DUF5401; Family of unknown function (DUF5401)

    6. XM_008763456.4 → XP_008761678.1  coiled-coil domain-containing protein 91 isoform X1

      See identical proteins and their annotated locations for XP_008761678.1

      UniProtKB/Swiss-Prot
      Q6AY97
      UniProtKB/TrEMBL
      A0A8I6G845
      Related
      ENSRNOP00000081556.1
      Conserved Domains (1) summary
      pfam17380
      Location:130 → 442
      DUF5401; Family of unknown function (DUF5401)

    7. XM_063286193.1 → XP_063142263.1  coiled-coil domain-containing protein 91 isoform X2

    8. XM_006237686.5 → XP_006237748.1  coiled-coil domain-containing protein 91 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A3R2, A0A8I6G845
      Related
      ENSRNOP00000087761.1
      Conserved Domains (1) summary
      pfam07851
      Location:149 → 256
      TMPIT; TMPIT-like protein

    9. XM_006237687.5 → XP_006237749.1  coiled-coil domain-containing protein 91 isoform X6

      UniProtKB/TrEMBL
      A0A8I6G845
      Conserved Domains (1) summary
      PTZ00121
      Location:113 → 340
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AY97.1 GenPept UniProtKB/Swiss-Prot:Q6AY97

    Gene LinkOut

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