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    TCP10L3 t-complex 10 like 3 (pseudogene) [ Homo sapiens (human) ]

    Gene ID: 6953, updated on 5-Mar-2024

    Summary

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    Official Symbol
    TCP10L3provided by HGNC
    Official Full Name
    t-complex 10 like 3 (pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:11656
    See related
    Ensembl:ENSG00000290751 MIM:187020; AllianceGenome:HGNC:11656
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    TCP10; TCP10A
    Annotation information
    Annotation category: suggests misassembly
    Expression
    Restricted expression toward testis (RPKM 4.5) See more
    Orthologs
    all
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    Genomic context

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    See TCP10L3 in Genome Data Viewer
    Location:
    6q27
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (167373090..167384510, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (168755727..168767109, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (167786578..167797998, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167738113-167738614 Neighboring gene tubulin tyrosine ligase like 2 Neighboring gene mitotic arrest deficient 2 like 1 pseudogene Neighboring gene Sharpr-MPRA regulatory region 6086 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167769573-167770114 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:167813964-167814643 Neighboring gene Sharpr-MPRA regulatory region 8873 Neighboring gene Sharpr-MPRA regulatory region 3778 Neighboring gene uncharacterized LOC105378126 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr6:167854012-167854880 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:167854881-167855750 Neighboring gene uncharacterized LOC105378127

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The human homolog of a candidate mouse t complex responder gene: conserved motifs and evolution with punctuated equilibria. Islam SD, et al. Hum Mol Genet, 1993 Dec. PMID 8111376
    2. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Joberty G, et al. Nat Cell Biol, 2000 Aug. PMID 10934474
    3. Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes? Nathan JA, et al. EMBO J, 2013 Feb 20. PMID 23314748, Free PMC Article
    4. Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease. Teixeira FR, et al. Biochem J, 2016 Oct 15. PMID 27503909, Free PMC Article
    5. The DNA sequence and analysis of human chromosome 6. Mungall AJ, et al. Nature, 2003 Oct 23. PMID 14574404

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Other Names

    • T-complex protein 10A homolog
    • t-complex 10 (a murine tcp homolog)
    • t-complex 10 homolog

    Clone Names

    • MGC34049

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_163193.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL592444
      Related
      ENST00000674952.1

    2. NR_163194.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL592444

    3. NR_163195.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL592444

    4. NR_163196.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL592444
      Related
      ENST00000617120.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      167373090..167384510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      168755727..168767109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001366311.1: Suppressed sequence

      Description
      NM_001366311.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    2. NM_001366312.1: Suppressed sequence

      Description
      NM_001366312.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    3. NM_001366313.1: Suppressed sequence

      Description
      NM_001366313.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    4. NM_001366317.1: Suppressed sequence

      Description
      NM_001366317.1: This RefSeq was removed because it is now thought that this gene is a pseudogene.

    5. NM_004610.3: Suppressed sequence

      Description
      NM_004610.3: This RefSeq was removed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version

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