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    Zfp983 zinc finger protein 983 [ Mus musculus (house mouse) ]

    Gene ID: 73229, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp983provided by MGI
    Official Full Name
    zinc finger protein 983provided by MGI
    Primary source
    MGI:MGI:1920479
    See related
    Ensembl:ENSMUSG00000035868 AllianceGenome:MGI:1920479
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mszf57; mszf71; 3110052M02Rik
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within response to bacterium. Predicted to be located in nuclear body and nucleolus. Predicted to be active in nucleus. Orthologous to human ZNF300 (zinc finger protein 300). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in whole brain E14.5 (RPKM 3.4), CNS E18 (RPKM 3.4) and 24 other tissues See more
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    Genomic context

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    See Zfp983 in Genome Data Viewer
    Location:
    17 A3.3; 17 11.4 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (21867183..21883882)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (21650572..21664966)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9942 Neighboring gene zinc finger protein 948 Neighboring gene predicted gene, 30531 Neighboring gene predicted gene, 41541 Neighboring gene predicted gene, 53991 Neighboring gene STARR-positive B cell enhancer ABC_E1933 Neighboring gene predicted gene 10509 Neighboring gene zinc finger protein 760

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR. Agata Y, et al. Gene, 1998 Jun 15. PMID 9630514
    2. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger protein 983

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001166497.1 → NP_001159969.1  zinc finger protein 983

      Status: VALIDATED

      Source sequence(s)
      MF597758
      Consensus CDS
      CCDS49994.1
      UniProtKB/TrEMBL
      E9PUT0
      Related
      ENSMUSP00000156443.2, ENSMUST00000232827.2
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    2. NM_001357098.1 → NP_001344027.1  zinc finger protein 983

      Status: VALIDATED

      Source sequence(s)
      BC064464, MF597758
      Consensus CDS
      CCDS49994.1
      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      21867183..21883882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017317669.3 → XP_017173158.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    2. XM_030250069.2 → XP_030105929.1  zinc finger protein 983 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:21 → 381
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304 → 324
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_030250067.2 → XP_030105927.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    4. XM_036160798.1 → XP_036016691.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    5. XM_030250066.2 → XP_030105926.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    6. XM_017317670.3 → XP_017173159.1  zinc finger protein 983 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:21 → 381
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304 → 324
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_030250068.2 → XP_030105928.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Related
      ENSMUSP00000039392.8, ENSMUST00000039726.8
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    8. XM_030250070.2 → XP_030105930.1  zinc finger protein 983 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:21 → 381
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:304 → 324
      ZF_C2H2; C2H2 Zn finger [structural motif]

    9. XM_036160799.1 → XP_036016692.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    10. XM_036160800.1 → XP_036016693.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box

    11. XM_036160801.1 → XP_036016694.1  zinc finger protein 983 isoform X1

      UniProtKB/TrEMBL
      E9PUT0
      Conserved Domains (3) summary
      COG5048
      Location:100 → 460
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:12 → 52
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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