MEF2A myocyte enhancer factor 2A [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: MEF2Aprovided by VGNC
Official Full Name: myocyte enhancer factor 2Aprovided by VGNC
Primary source: VGNC:VGNC:74698
See related: Ensembl:ENSMMUG00000018122
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (78767335..78928601)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	7	NC_027899.1 (78225780..78386855)

Chromosome 7 - NC_041760.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

D15S907 (e-PCR)
- UniSTS:279

SHGC-75886 (e-PCR)
- UniSTS:12336

G32497 (e-PCR)
- UniSTS:117082

D15S901 (e-PCR)
- UniSTS:13157

RH15752 (e-PCR)
- UniSTS:60281

Mef2a (e-PCR), detects polymorphism
- UniSTS:265599

Mef2a (e-PCR), detects polymorphism
- UniSTS:265600

Mef2a (e-PCR), detects polymorphism
- UniSTS:265601

A009F05 (e-PCR)
- UniSTS:3465

D1S3692 (e-PCR)
- UniSTS:474270

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables histone deacetylase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in heart development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: myocyte-specific enhancer factor 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001260914.1 → NP_001247843.1 myocyte-specific enhancer factor 2A

See identical proteins and their annotated locations for NP_001247843.1

Status: PROVISIONAL

Source sequence(s)

JV047086

UniProtKB/TrEMBL

H9FUJ3

Related

ENSMMUP00000023816.4, ENSMMUT00000025457.4

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041760.1 Reference Mmul_10 Primary Assembly

Range

78767335..78928601

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028850378.1 → XP_028706211.1 myocyte-specific enhancer factor 2A isoform X6

Conserved Domains (2) summary

pfam12347
Location:29 → 88

HJURP_C; Holliday junction regulator protein family C-terminal repeat

cl00109
Location:2 → 18

MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...
XM_015143130.2 → XP_014998616.1 myocyte-specific enhancer factor 2A isoform X1

UniProtKB/TrEMBL

A0A1D5R1Y7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 156

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_015143134.2 → XP_014998620.1 myocyte-specific enhancer factor 2A isoform X2

UniProtKB/TrEMBL

H9FUJ5

Conserved Domains (3) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam11597
Location:129 → 238

Med13_N; Mediator complex subunit 13 N-terminal

pfam12347
Location:98 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_015143137.2 → XP_014998623.1 myocyte-specific enhancer factor 2A isoform X5

UniProtKB/TrEMBL

A0A1D5R1Y7, F7FGA1, H9FUJ6

Related

ENSMMUP00000054321.2, ENSMMUT00000079107.2

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 150

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_028850379.1 → XP_028706212.1 myocyte-specific enhancer factor 2A isoform X7

Conserved Domains (2) summary

pfam12347
Location:29 → 82

HJURP_C; Holliday junction regulator protein family C-terminal repeat

cl00109
Location:2 → 25

MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...
XM_028850380.1 → XP_028706213.1 myocyte-specific enhancer factor 2A isoform X8

Conserved Domains (2) summary

pfam12347
Location:29 → 82

HJURP_C; Holliday junction regulator protein family C-terminal repeat

cl00109
Location:2 → 25

MADS; MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type ...
XM_015143136.2 → XP_014998622.1 myocyte-specific enhancer factor 2A isoform X4

UniProtKB/TrEMBL

F7FGB3

Related

ENSMMUP00000023814.2, ENSMMUT00000025455.4

Conserved Domains (3) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam11597
Location:129 → 238

Med13_N; Mediator complex subunit 13 N-terminal

pfam12347
Location:98 → 152

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_015143135.2 → XP_014998621.1 myocyte-specific enhancer factor 2A isoform X3

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:98 → 156

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_028850376.1 → XP_028706209.1 myocyte-specific enhancer factor 2A isoform X1

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 156

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_015143131.2 → XP_014998617.1 myocyte-specific enhancer factor 2A isoform X1

UniProtKB/TrEMBL

A0A1D5R1Y7

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 156

HJURP_C; Holliday junction regulator protein family C-terminal repeat
XM_028850377.1 → XP_028706210.1 myocyte-specific enhancer factor 2A isoform X1

Conserved Domains (2) summary

cd00265
Location:2 → 78

MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...

pfam12347
Location:97 → 156

HJURP_C; Holliday junction regulator protein family C-terminal repeat