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    Exoc6b exocyst complex component 6B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500233, updated on 6-Jun-2024

    Summary

    Official Symbol
    Exoc6bprovided by RGD
    Official Full Name
    exocyst complex component 6Bprovided by RGD
    Primary source
    RGD:1560638
    See related
    Ensembl:ENSRNOG00000059615 AllianceGenome:RGD:1560638
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560638
    Summary
    Predicted to be involved in intracellular protein transport; vesicle docking involved in exocytosis; and vesicle tethering involved in exocytosis. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 3. Orthologous to human EXOC6B (exocyst complex component 6B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 79.9), Lung (RPKM 61.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Exoc6b in Genome Data Viewer
    Location:
    4q34
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (118652279..119107725, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (117094741..117550221, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (116314695..116786466, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene cytochrome P450, family 26, subfamily b, polypeptide 1 Neighboring gene small nucleolar RNA U13 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene sperm motility kinase X like, pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC189077

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle tethering involved in exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    exocyst complex component 6B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109246.3NP_001102716.1  exocyst complex component 6B

      See identical proteins and their annotated locations for NP_001102716.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000004
      UniProtKB/TrEMBL
      A0A0G2JYR1, A0A8I6A6E0, A6IAR0
      Related
      ENSRNOP00000070757.1, ENSRNOT00000091490.2
      Conserved Domains (1) summary
      pfam04091
      Location:464770
      Sec15; Exocyst complex subunit Sec15-like

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      118652279..119107725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286527.1XP_063142597.1  exocyst complex component 6B isoform X2

    2. XM_063286526.1XP_063142596.1  exocyst complex component 6B isoform X1

      UniProtKB/TrEMBL
      A0A8I6A6E0, A0A8I6APB7