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    K10D3.4 BPTI/Kunitz inhibitor domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172452, updated on 7-Sep-2023

    Summary

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    Gene symbol
    K10D3.4
    Gene description
    BPTI/Kunitz inhibitor domain-containing protein
    Primary source
    WormBase:WBGene00010738
    Locus tag
    CELE_K10D3.4
    See related
    AllianceGenome:WB:WBGene00010738
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See K10D3.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (7134738..7139898, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene RUN domain-containing protein Neighboring gene TAFII28-like protein domain-containing protein Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein Neighboring gene FErroChelatase-Like Neighboring gene CARMIL pleckstrin homology domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Paek J, et al. Cell Metab, 2012 Oct 3. PMID 23040073, Free PMC Article
    2. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Duchaine TF, et al. Cell, 2006 Jan 27. PMID 16439208
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BPTI/Kunitz inhibitor domain-containing protein
    NP_492020.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7134738..7139898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059619.5 → NP_492020.1  BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492020.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21418
      Conserved Domains (3) summary
      smart00131
      Location:312 → 352
      KU; BPTI/Kunitz family of serine protease inhibitors
      pfam00014
      Location:410 → 462
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam01683
      Location:46 → 100
      EB; EB module
    Nucleotide Protein
    Heading Accession and Version

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