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    idi-1 isopentenyl-diphosphate Delta-isomerase [ Caenorhabditis elegans ]

    Gene ID: 176142, updated on 23-May-2024

    Summary

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    Gene symbol
    idi-1
    Gene description
    isopentenyl-diphosphate Delta-isomerase
    Primary source
    WormBase:WBGene00019460
    Locus tag
    CELE_K06H7.9
    See related
    AllianceGenome:WB:WBGene00019460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable isopentenyl-diphosphate delta-isomerase activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process. Predicted to be active in cytoplasm. Orthologous to several human genes including IDI2 (isopentenyl-diphosphate delta isomerase 2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See idi-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (8091708..8093042)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene GTP exchange factor for ARFs 1 Neighboring gene tRNA endonuclease vms-1 Neighboring gene Uncharacterized protein Neighboring gene Putative serine/threonine-protein kinase K06H7.1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans. Yochem J, et al. Mol Genet Genomics, 2005 Apr. PMID 15765206
    2. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isopentenyl-diphosphate delta-isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables isopentenyl-diphosphate delta-isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in dimethylallyl diphosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in isopentenyl diphosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    isopentenyl-diphosphate Delta-isomerase
    NP_001379667.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8091708..8093042
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392149.1 → NP_001379667.1  isopentenyl-diphosphate Delta-isomerase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFQ1
      Conserved Domains (1) summary
      cd02885
      Location:32 → 209
      IPP_Isomerase; Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated ...
    Nucleotide Protein
    Heading Accession and Version

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