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    rcan1b regulator of calcineurin 1b [ Danio rerio (zebrafish) ]

    Gene ID: 336348, updated on 27-Mar-2024

    Summary

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    Official Symbol
    rcan1bprovided by ZNC
    Official Full Name
    regulator of calcineurin 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8292
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-8292
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dscr1; rcan1; wu:fr92c05
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to act upstream of or within calcineurin-NFAT signaling cascade. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human RCAN1 (regulator of calcineurin 1). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    all
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    Genomic context

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    See rcan1b in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) Unplaced Scaffold NW_003334033.1 (12432..22011)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_003334033.1 (9626..20076)

    NW_003334033.1Genomic Context describing neighboring genes

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. Alejevski F, et al. Open Biol, 2021 Aug. PMID 34375549, Free PMC Article
    2. Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish. Cho HJ, et al. Dis Model Mech, 2019 May 23. PMID 31043432, Free PMC Article
    3. A comparative map of the zebrafish genome. Woods IG, et al. Genome Res, 2000 Dec. PMID 11116086, Free PMC Article
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    calcipressin-1; LOW QUALITY PROTEIN: calcipressin-1
    Names
    Down syndrome critical region gene 1
    regulator of calcineurin 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NW_003334033.1 Reference GRCz11 Primary Assembly

      Range
      12432..22011
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470802.1 → XP_021326477.1  LOW QUALITY PROTEIN: calcipressin-1

      UniProtKB/TrEMBL
      A0A8M9P730
      Conserved Domains (1) summary
      cl17169
      Location:33 → 201
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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