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    LOC127827406 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:36986696-36987694 [ Homo sapiens (human) ]

    Gene ID: 127827406, updated on 10-Oct-2023

    Summary

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    Gene symbol
    LOC127827406
    Gene description
    H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:36986696-36987694
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Nov 2022]
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    Genomic context

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    See LOC127827406 in Genome Data Viewer
    Location:
    chromosome: 14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (36517491..36518489)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (30706766..30707773)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene DPPA3 pseudogene 2 Neighboring gene RNA, U7 small nuclear 93 pseudogene Neighboring gene VISTA enhancer hs1538 Neighboring gene VISTA enhancer hs704 Neighboring gene surfactant associated 3 Neighboring gene VISTA enhancer hs1166 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36974689-36975264 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr14:36977998-36978653 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36983846-36984473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36988853-36989852 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36989853-36990852 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36990853-36991852 Neighboring gene NKX2-1 antisense RNA 1 Neighboring gene uncharacterized LOC105370453 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:36994071-36995009 Neighboring gene NK2 homeobox 1 Neighboring gene phosphorylase kinase regulatory subunit beta pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_128910.1 

      Range
      101..1099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      36517491..36518489
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      30706766..30707773
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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