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    CPB cathepsin L-like protease [ Leishmania braziliensis MHOM/BR/75/M2904 ]

    Gene ID: 5412985, updated on 28-Dec-2023

    Summary

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    Gene symbol
    CPB
    Gene description
    cathepsin L-like protease
    Locus tag
    LBRM_08_0830
    Gene type
    protein coding
    RNA name
    cathepsin L-like protease
    RefSeq status
    PROVISIONAL
    Organism
    Leishmania braziliensis MHOM/BR/75/M2904 (strain: MHOM/BR/75/M2904)
    Lineage
    Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Leishmaniinae; Leishmania; Leishmania braziliensis species complex
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    Genomic context

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    Location:
    chromosome: 8
    Exon count:
    1
    Sequence:
    Chromosome: 8; NC_009300.2 (329644..330969, complement)

    Chromosome 8 - NC_009300.2Genomic Context describing neighboring genes Neighboring gene cathepsin L-like protease Neighboring gene cathepsin L-like protease Neighboring gene putative histone deacetylase Neighboring gene hypothetical protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_009300.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Peacock CS, et al. Nat Genet, 2007 Jul. PMID 17572675, Free PMC Article
    2. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Rogers MB, et al. Genome Res, 2011 Dec. PMID 22038252, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Names
    cathepsin L-like protease

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_009300.2 Reference assembly

      Range
      329644..330969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001562091.1 → XP_001562141.1  cathepsin L-like protease [Leishmania braziliensis MHOM/BR/75/M2904]

      See identical proteins and their annotated locations for XP_001562141.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3P3YYY9, A4H5E6
      Conserved Domains (4) summary
      PTZ00203
      Location:1 → 339
      PTZ00203; cathepsin L protease; Provisional
      smart00848
      Location:38 → 93
      Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
      pfam00112
      Location:126 → 338
      Peptidase_C1; Papain family cysteine protease
      pfam12131
      Location:353 → 415
      DUF3586; Protein of unknown function (DUF3586)
    Nucleotide Protein
    Heading Accession and Version

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