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    DGKA diacylglycerol kinase alpha [ Crotalus tigris (Tiger rattlesnake) ]

    Gene ID: 120300572, updated on 21-Mar-2024

    Summary

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    Gene symbol
    DGKA
    Gene description
    diacylglycerol kinase alpha
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Crotalus tigris
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024100514.1 (1644725..1731482, complement)

    NW_024100514.1Genomic Context describing neighboring genes Neighboring gene cyclin dependent kinase 2 Neighboring gene premelanosome protein Neighboring gene dendrin Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024100514 Unplaced Scaffold Reference ASM1654583v1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in diacylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diacylglycerol kinase alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1654583v1

    Genomic

    1. NW_024100514.1 Reference ASM1654583v1

      Range
      1644725..1731482 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039326779.1 → XP_039182713.1  diacylglycerol kinase alpha

      Conserved Domains (6) summary
      smart00045
      Location:524 → 705
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:382 → 503
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:117 → 186
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam14513
      Location:6 → 113
      DAG_kinase_N; Diacylglycerol kinase N-terminus
      cd20799
      Location:204 → 264
      C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
      cd20890
      Location:274 → 335
      C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

    2. XM_039326778.1 → XP_039182712.1  diacylglycerol kinase alpha

      Conserved Domains (6) summary
      smart00045
      Location:524 → 705
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:382 → 503
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:117 → 186
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam14513
      Location:6 → 113
      DAG_kinase_N; Diacylglycerol kinase N-terminus
      cd20799
      Location:204 → 264
      C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
      cd20890
      Location:274 → 335
      C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

    3. XM_039326780.1 → XP_039182714.1  diacylglycerol kinase alpha

      Conserved Domains (6) summary
      smart00045
      Location:524 → 705
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:382 → 503
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:117 → 186
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam14513
      Location:6 → 113
      DAG_kinase_N; Diacylglycerol kinase N-terminus
      cd20799
      Location:204 → 264
      C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
      cd20890
      Location:274 → 335
      C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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