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    SMAD7 SMAD family member 7 [ Homo sapiens (human) ]

    Gene ID: 4092, updated on 5-May-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Circular RNA circWNK1 inhibits the progression of gastric cancer via regulating the miR-21-3p/SMAD7 axis.

    Circular RNA circWNK1 inhibits the progression of gastric cancer via regulating the miR-21-3p/SMAD7 axis.
    Dai T, Qiu S, Gao X, Zhao C, Ge Z, Yang Y, Tang C, Feng S., Free PMC Article

    03/13/2024
    SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors.

    SMAD7 expression in CAR-T cells improves persistence and safety for solid tumors.
    Liang S, Zheng R, Zuo B, Li J, Wang Y, Han Y, Dong H, Zhao X, Zhang Y, Wang P, Meng R, Jia L, Yang A, Yan B.,

    03/1/2024
    SMAD7 gene polymorphisms and their influence on patients with colorectal cancer.

    SMAD7 gene polymorphisms and their influence on patients with colorectal cancer.
    Wu Y, Xu J, Tan B, Yi T, Liu S, Yang G, Li K, Zhao X.,

    02/2/2024
    Circular RNA sirtuin-1 restrains the malignant phenotype of non-small cell lung cancer cells via the microRNA-510-5p/SMAD family member 7 axis.

    Circular RNA sirtuin-1 restrains the malignant phenotype of non-small cell lung cancer cells via the microRNA-510-5p/SMAD family member 7 axis.
    Zhao Z, Zhang H, Zhang F, Ji Y, Peng Y, Wang F, Zhao L.

    01/3/2024
    Identification and characterization of colorectal-cancer-associated SNPs on the SMAD7 locus.

    Identification and characterization of colorectal-cancer-associated SNPs on the SMAD7 locus.
    Liu Z, Zhao Y, Song H, Miao H, Wang Y, Tu C, Fu T, Qin J, Du B, Qian M, Ren H.

    11/20/2023
    [Silencing of SMAD family member 3 promotes M2 polarization of macrophages and the expression of SMAD7 in rheumatoid arthritis].

    [Silencing of SMAD family member 3 promotes M2 polarization of macrophages and the expression of SMAD7 in rheumatoid arthritis].
    Fei C, Shen X, Wan L, Fan H, Liu T, Li M, Liu L, Ge Y, Wang Q, Fan W, Zhou Q.

    11/14/2023
    TGF-beta1 signaling and Smad7 control T-cell responses in health and immune-mediated disorders.

    TGF-β1 signaling and Smad7 control T-cell responses in health and immune-mediated disorders.
    Laudisi F, Stolfi C, Monteleone I, Monteleone G.

    11/6/2023
    CircMACF1 alleviates myocardial fibrosis after acute myocardial infarction by suppressing cardiac fibroblast activation via the miR-16-5p/SMAD7 axis.

    CircMACF1 alleviates myocardial fibrosis after acute myocardial infarction by suppressing cardiac fibroblast activation via the miR-16-5p/SMAD7 axis.
    Wang Y, Liu Y, Fei A, Tan L., Free PMC Article

    09/23/2023
    Are SMAD2/4/7 genetic variants associated with rheumatoid arthritis susceptibility and severity?

    Are SMAD2/4/7 genetic variants associated with rheumatoid arthritis susceptibility and severity?
    Wajda A, Stypińska B, Czarnecka M, Hasan D, Jarończyk M, Haładyj E, Romanowska-Próchnicka K, Olesińska M, Pawlik A, Paradowska-Gorycka A.

    09/12/2023
    Overexpression of SMAD7 improves the function of EGFR-targeted human CAR-T cells against non-small-cell lung cancer.

    Overexpression of SMAD7 improves the function of EGFR-targeted human CAR-T cells against non-small-cell lung cancer.
    Li G, Liao G, Xie J, Liu B, Li X, Qiu M.

    08/22/2023
    YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.

    YES-associated protein-regulated Smad7 worsen epithelial barrier injury of chronic sinusitis with nasal polyps.
    Jiang X, Shu L, Liu Y, Shen Y, Ke X, Liu J, Yang Y., Free PMC Article

    07/7/2023
    Hypermethylation of Smad7 in CD4[+] T cells is associated with the disease activity of rheumatoid arthritis.

    Hypermethylation of Smad7 in CD4(+) T cells is associated with the disease activity of rheumatoid arthritis.
    Hu Y, Xu B, He J, Shan H, Zhou G, Wang D, Bai L, Shang H, Nie L, Pan F, Lan HY, Wang Q., Free PMC Article

    03/2/2023
    Genetic analysis and allele-specific expression of SMAD7 3'UTR variants in human colorectal cancer reveal a novel somatic variant exhibiting allelic imbalance.

    Genetic analysis and allele-specific expression of SMAD7 3'UTR variants in human colorectal cancer reveal a novel somatic variant exhibiting allelic imbalance.
    Rosic J, Miladinov M, Dragicevic S, Eric K, Bogdanovic A, Krivokapic Z, Nikolic A.

    02/22/2023
    Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case-control studies.

    Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case-control studies.
    Xiao Q, Chen J, Zhu J, Zeng S, Cai H, Zhu G., Free PMC Article

    01/28/2023
    HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.

    HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation.
    Gao Y, Liu Y, Zheng D, Ho C, Wen D, Sun J, Huang L, Liu Y, Li Q, Zhang Y., Free PMC Article

    10/29/2022
    Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1beta-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.

    Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
    Li B, Lu ZY, Jiang SD, Jiang LS, Zheng XF., Free PMC Article

    07/23/2022
    Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk.

    Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk.
    Alidoust M, Hamzehzadeh L, Khorshid Shamshiri A, Afzaljavan F, Kerachian MA, Fanipakdel A, Aledavood SA, Allahyari A, Bari A, Moosanen Mozaffari H, Goshayeshi L, Pasdar A., Free PMC Article

    04/16/2022
    Targeting of Smad7 in Mesenchymal Cells Does Not Exacerbate Fibrosis During Experimental Chronic Pancreatitis.

    Targeting of Smad7 in Mesenchymal Cells Does Not Exacerbate Fibrosis During Experimental Chronic Pancreatitis.
    Li X, Nania S, Kleiter I, Löhr JM, Heuchel RL.

    03/26/2022
    Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.

    Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
    Guo Y, Gao X, An S, Li X, Pan L, Liu H, Liu J, Gao J, Zhao Z, Li G, Han Y, Li Y, Ji Z., Free PMC Article

    02/5/2022
    miR-21-5p/SMAD7 axis promotes the progress of lung cancer.

    miR-21-5p/SMAD7 axis promotes the progress of lung cancer.
    Tang J, Li X, Cheng T, Wu J., Free PMC Article

    01/29/2022
    Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.

    Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans.
    Wang H, Song X, Liao H, Wang P, Zhang Y, Che L, Zhang J, Zhou Y, Cigliano A, Ament C, Superville D, Ribback S, Reeves M, Pes GM, Liang B, Wu H, Evert M, Calvisi DF, Zeng Y, Chen X., Free PMC Article

    01/8/2022
    Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patients.

    Smad7 down-regulation via ubiquitin degradation mediated by Smurf2 in fibroblasts of hypertrophic scars in burned patients.
    Zhang Z, Liu C, Chen B, Tang W, Liu Z, Cao W, Li X.

    12/25/2021
    FOXD3 suppresses epithelial-mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma.

    FOXD3 suppresses epithelial-mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma.
    Wu Z, Li Y, Niu Y, Lu J, Yan Z, Xu T, Guo Y, Dong Z, Guo W.

    12/25/2021
    Overexpression of BAMBI and SMAD7 impacts prognosis of acute myeloid leukemia patients: A potential TERT non-canonical role.

    Overexpression of BAMBI and SMAD7 impacts prognosis of acute myeloid leukemia patients: A potential TERT non-canonical role.
    Shehata MM, Sallam AM, Naguib MG, El-Mesallamy HO.

    12/25/2021
    SMAD7 and SMAD4 expression in colorectal cancer progression and therapy response.

    SMAD7 and SMAD4 expression in colorectal cancer progression and therapy response.
    Rosic J, Dragicevic S, Miladinov M, Despotovic J, Bogdanovic A, Krivokapic Z, Nikolic A.

    12/25/2021
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