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    LOC127884557 H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287896-75288436 [ Homo sapiens (human) ]

    Gene ID: 127884557, updated on 10-Oct-2023

    Summary

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    Gene symbol
    LOC127884557
    Gene description
    H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287896-75288436
    Gene type
    biological region
    Feature type(s)
    regulatory: enhancer
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in primed human embryonic stem cells. This enhancer is marked by the H3K27ac and H3K4me1 histone modifications. [provided by RefSeq, Dec 2022]
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    Genomic context

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    See LOC127884557 in Genome Data Viewer
    Location:
    chromosome: 16
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (75253998..75254538)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (81300747..81301287)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene chymotrypsinogen B1 Neighboring gene uncharacterized LOC100506281 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75267182-75267807 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7711 Neighboring gene BCAR1 scaffold protein, Cas family member Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75270483-75271324 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75272167-75273008 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75274691-75275532 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75275533-75276374 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11126 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75281985-75282648 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7712 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7713 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75285734-75286274 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75286815-75287355 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75287356-75287895 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75288976-75289516 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75289517-75290056 Neighboring gene uncharacterized LOC105371344 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75290057-75290597 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:75294897-75295696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75297293-75298090 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75298091-75298888 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7714 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7715 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7716 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7717 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7718 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:75305973-75306511 Neighboring gene RNA, U6 small nuclear 758, pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells. Barakat TS, et al. Cell Stem Cell, 2018 Aug 2. PMID 30033119, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_134335.1 

      Range
      101..641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      75253998..75254538
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      81300747..81301287
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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