Genome

Saccharomyces cerevisiae (brewer's yeast) Baker's yeast, brewer's yeast Lineage: Eukaryota[15557]; Fungi[5220]; Dikarya[4853]; Ascomycota[3867]; Saccharomycotina[1194]; Saccharomycetes[1194]; Saccharomycetales[1193]; Saccharomycetaceae[156]; Saccharomyces[20]; Saccharomyces cerevisiae[1]

The budding yeast Saccharomyces cerevisiae is one of the major model organisms for understanding cellular and molecular processes in eukaryotes. This single-celled organism is also important in industry, where it is used to make bread, beer, wine, enzymes, and pharmaceuticals.The Saccharomyces cerevisiae genome is approximately 12 Mb, organized in 16 chromosomes.

Summary Sequence data:  genome assemblies: 1553; sequence reads: 233  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 11.8605  median protein count: 5659  median GC%: 38.2 Publications (limited to 20 most recent records) Long-read direct RNA sequencing of the mitochondrial transcriptome of Saccharomyces cerevisiae reveals condition-dependent intron abundance. Koster CC, et al. Yeast 2024 Apr Chromosome-dependent aneuploid formation in Spo11-less meiosis. Kawashima Y, et al. Genes Cells 2023 Feb Recovery of 197 eukaryotic bins reveals major challenges for eukaryote genome reconstruction from terrestrial metagenomes. Saraiva JP, et al. Mol Ecol Resour 2023 Jul New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources. Engel SR, et al. Genetics 2022 Apr 4 Benchmarking of long-read sequencing, assemblers and polishers for yeast genome. Zhang X, et al. Brief Bioinform 2022 May 13 Resistance to Arsenite and Arsenate in Saccharomyces cerevisiae Arises through the Subtelomeric Expansion of a Cluster of Yeast Genes. Stefanini I, et al. Int J Environ Res Public Health 2022 Jul 1 A supernumerary designer chromosome for modular in vivo pathway assembly in Saccharomyces cerevisiae. Postma ED, et al. Nucleic Acids Res 2021 Feb 22 Adaptive Gene Content and Allele Distribution Variations in the Wild and Domesticated Populations of Saccharomyces cerevisiae. Han DY, et al. Front Microbiol 2021 Comparative Genomics Supports That Brazilian Bioethanol Saccharomyces cerevisiae Comprise a Unified Group of Domesticated Strains Related to Cachaça Spirit Yeasts. Jacobus AP, et al. Front Microbiol 2021 Secondary Metabolites from Food-Derived Yeasts Inhibit Virulence of Candida albicans. Kunyeit L, et al. mBio 2021 Aug 31 Two Synthetic 18-Way Outcrossed Populations of Diploid Budding Yeast with Utility for Complex Trait Dissection. Linder RA, et al. Genetics 2020 Jun Complete Genome Sequence of the Citrobacter freundii Type Strain. Wan KH, et al. Microbiol Resour Announc 2020 May 7 A natural variant of the essential host gene MMS21 restricts the parasitic 2-micron plasmid in Saccharomyces cerevisiae. Hays M, et al. Elife 2020 Oct 16 Single-molecule sequencing detection of N6-methyladenine in microbial reference materials. McIntyre ABR, et al. Nat Commun 2019 Feb 4 FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science. Sichtig H, et al. Nat Commun 2019 Jul 25 Construction of industrial Saccharomyces cerevisiae strains for the efficient consolidated bioprocessing of raw starch. Cripwell RA, et al. Biotechnol Biofuels 2019 Reshuffling yeast chromosomes with CRISPR/Cas9. Fleiss A, et al. PLoS Genet 2019 Aug Probiotic Yeasts Inhibit Virulence of Non-albicans Candida Species. Kunyeit L, et al. mBio 2019 Oct 15 Fermentation innovation through complex hybridization of wild and domesticated yeasts. Langdon QK, et al. Nat Ecol Evol 2019 Nov The origin and adaptive evolution of domesticated populations of yeast from Far East Asia. Duan SF, et al. Nat Commun 2018 Jul 12 More...  Representative (genome information for reference and representative genomes) Reference genome:   Saccharomyces cerevisiae S288C Submitter: Saccharomyces Genome Database Loc Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr I NC_001133.9 BK006935.2 0.23 39.3 94 - 4 2 101 1 Chr II NC_001134.8 BK006936.2 0.81 38.3 416 - 13 6 435 - Chr III NC_001135.5 BK006937.2 0.32 38.5 168 - 10 4 184 2 Chr IV NC_001136.10 BK006938.2 1.53 37.9 766 - 28 4 799 1 Chr V NC_001137.3 BK006939.2 0.58 38.5 288 - 20 9 318 1 Chr VI NC_001138.5 BK006940.2 0.27 38.7 128 - 10 4 143 1 Chr VII NC_001139.9 BK006941.2 1.09 38.1 540 - 36 10 586 - Chr VIII NC_001140.6 BK006934.2 0.56 38.5 292 - 11 5 308 - Chr IX NC_001141.2 BK006942.2 0.44 38.9 213 - 10 3 232 6 Chr X NC_001142.9 BK006943.2 0.75 38.4 365 - 24 6 395 - Chr XI NC_001143.9 BK006944.2 0.67 38.1 318 - 16 5 339 - Chr XII NC_001144.5 BK006945.2 1.08 38.5 520 12 21 18 573 2 Chr XIII NC_001145.3 BK006946.2 0.92 38.2 471 - 21 16 508 - Chr XIV NC_001146.8 BK006947.3 0.78 38.6 398 - 14 6 418 - Chr XV NC_001147.6 BK006948.2 1.09 38.2 546 - 20 11 579 2 Chr XVI NC_001148.4 BK006949.2 0.95 38.1 474 - 17 7 500 2 MT NC_001224.1 - 0.09 17.1 19 2 24 1 46 - Chromosomes Click on chromosome name to open Genome Data Viewer External Resources Fungal Genome Initiative White Paper #2 White Paper: Resequencing Multiple strains of Saccharomyces cerevisiae Saccharomyces Genome Database (SGD) MIPS Comprehensive Yeast Genome Database (CYGD) Saccharomyces cerevisiae GeneDB DFCI S. cerevisiae Gene Index Broad Institute Tree of life web project