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| Status |
Public on Feb 08, 2008 |
| Title |
Expression profiling of mammalian Schwann cells in response to NF1 RNAi treatment and the MEK inhibitor U0126 |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
Comparison of the changes in the gene expression profile of cells in which NF1 has been knocked down by RNAi in the presence/absence of the MEK inhibitor UO126
Keywords: RNAi knock-down of NF1 gene
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| Overall design |
Primary Rat Schwann cells were transiently transfected with either scrambled (control) or NF1 RNAi oligonucleotides in the presence/absence of the MEK inhibitor UO126. Total RNA was then harvested 48 hours post-transfection. Three independent biological replicates were analysed.
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| |
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| Contributor(s) |
Parrinello S, Noon LA, Echave P, Lloyd AC, Harrisingh MC, Wingfield-Digby P, Cremona C, Rosenberg L, Flanagan A, Parada LF |
| Citation missing |
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| Submission date |
Feb 04, 2008 |
| Last update date |
Jul 31, 2017 |
| Contact name |
Luke Adam Noon |
| E-mail(s) |
l.noon@ucl.ac.uk
|
| Phone |
02076797261
|
| Fax |
02076797805
|
| Organization name |
MRC
|
| Department |
LMCB
|
| Lab |
Lloyd
|
| Street address |
Gower Street
|
| City |
London |
| ZIP/Postal code |
WC1E 6BT |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA108113 |
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