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| Status |
Public on Feb 07, 2018 |
| Title |
Murine epiSC control vs murine epiSC differentiated into dopaminergic neurons [miRNA] |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Small-RNA profiling of mouse embryonic, epiblast-derived, stem cells (epiSC). epiSC differentiated towards the dopaminergic phenotype were compared to control untreated epiSC. EpiSc were derived from a Pitx3-GFP mouse allowing visualization of dopaminergic (GFP+) differentiation efficiency.
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| Overall design |
EpiSC derived from Pitx3-GFP mice were differentiated for fourteen days. Dopaminergic diffferentiation starts at day 5 with the addition of morphogens SHH and FGF8. Control cells were growth in absence of morphogens. Samples were collected in triplicate at day 5 (before the addition of SHH/FGF) and at day 9 and day 14 for both control and treated cells.
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| Contributor(s) |
Costa V, Bellenchi GC, Li M, Greco D |
| Citation(s) |
29526736 |
| Submission date |
Feb 07, 2018 |
| Last update date |
May 09, 2018 |
| Contact name |
Valerio Costa |
| E-mail(s) |
valerio.costa@igb.cnr.it
|
| Phone |
+390816132617
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| Organization name |
National Research Council
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| Department |
Institute of Genetics and Biophysics
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| Street address |
Via P. Castellino, 111
|
| City |
Naples |
| State/province |
Italy |
| ZIP/Postal code |
80131 |
| Country |
Italy |
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| Platforms (1) |
| GPL24547 |
Agilent-038112 mouse miRNA microarray, Release 18.0 (Probe ID version) |
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| Samples (15)
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| This SubSeries is part of SuperSeries: |
| GSE110270 |
Murine epiSC control vs murine epiSC differentiated into dopaminergic neurons |
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| Relations |
| BioProject |
PRJNA433346 |
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