|
| Status |
Public on Apr 17, 2019 |
| Title |
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
LncRNA-IIRX plays critical role in Bcr-Abl-induced tumorigenesis. To discover its mechanisms underlying cellular transformation by Bcr-Abl oncogene, genome-wide mRNA expression was measured by RNA-seq in K562 cells expressing shRNA targeting lncRNA-IIRX and control cells. We identified many genes with differential expression in K562 cells after knocking down lncRNA-IIRX.
|
| |
|
| Overall design |
RNA samples from K562 cells expressing shRNA targeting lncRNA-IIRX and control cells were collected. Six total RNA samples from three independent experiments were extracted and used for RNA-seq.
|
| |
|
| Contributor(s) |
Wang X, Chen J |
| Citation(s) |
30961617 |
| Submission date |
Sep 22, 2018 |
| Last update date |
Apr 17, 2019 |
| Contact name |
Xuefei Wang |
| E-mail(s) |
wangxf09sk@126.com
|
| Phone |
18810357854
|
| Organization name |
nstitute of Microbiology, Chinese Academy of Sciences (CAS)
|
| Lab |
1. CAS Key Laboratory of Pathogenic Microbiology and Immunology
|
| Street address |
NO.1 West Beichen Road, Chaoyang District, Beijing 100101, China
|
| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100101 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA492752 |
| SRA |
SRP162384 |
Less...
More...