|
| Status |
Public on Oct 25, 2018 |
| Title |
IL-12 and IL-23 dependent gene induction in purified CD19+, CD8+, CD4+, gdTCR+ and CD56+ cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The aim of this experiment was to study IL-12 and IL-23 dependent gene induction in different immune cell types in order to assess where these two pathways converge and diverge
|
| |
|
| Overall design |
CD19+, CD8+, CD4+, gdTCR+ and CD56+ cells were purified by MACS or sorting and stimulated with IL-12 (20ng/ml) or IL-23 (100ng/ml)
|
| |
|
| Contributor(s) |
Casanova J, Martinez-Barricarte R, Markle J |
| Citation(s) |
30578351 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R37 AI095983 |
Genome-Wide Dissection of Mendelian Susceptibility to Mycobacterial Disease |
THE ROCKEFELLER UNIVERSITY |
Jean-Laurent Casanova |
| R01 AI089970 |
A genetic dissection of Mendelian susceptibility to mycobacterial diseases (MSMD) |
THE ROCKEFELLER UNIVERSITY |
Jean-Laurent Casanova |
| K99 AI127932 |
Human genetic determinants of mycobacterial immunity |
THE ROCKEFELLER UNIVERSITY |
Janet Markle |
| UL1 TR001866 |
Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success |
THE ROCKEFELLER UNIVERSITY |
Barry Coller |
| UL1 TR000043 |
Transforming Translational Science and Education to Benefit Human Health |
THE ROCKEFELLER UNIVERSITY |
Barry Coller |
|
| Submission date |
Oct 04, 2018 |
| Last update date |
Jan 24, 2019 |
| Contact name |
Yelena Nemirovskaya |
| E-mail(s) |
yene399@rockefeller.edu
|
| Organization name |
Rockefeller University
|
| Lab |
St. Giles Laboratory of Human Genetics of Infectious Diseases
|
| Street address |
1230 York Avenue
|
| City |
New York |
| ZIP/Postal code |
NY 10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17586 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
| Samples (15)
|
|
| Relations |
| BioProject |
PRJNA494701 |
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