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| Status |
Public on Nov 07, 2018 |
| Title |
chrRNA-seq in wild-type, SmcHD1 MommeD1mut and somKO MEFs |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this study we investigate the role of the non-canonical SMC family protein, SmcHD1in the X inactivation.
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| Overall design |
Set of allele-specific chromatin RNA-seq experiments on female clonal inter-specific (M.m.domesticus FVB x M.m.Castaneus) MEF cell lines: wild-type MEFs, SmcHD1 MomeD1 mut MEFs (SmcHD1 null) and SmcHD1 CRISPR KO MEFs (derived from wild-type MEFs after establishemnt of X inactivation).
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| Contributor(s) |
Gdula MR, Nesterova TB, Pintacuda G, Godwin J, McClellan M, Kriaucionis S, Krueger F, Reik W, Zhan Y, Ozadam H, Dekker J, Green CM, Moralli D, Heard E, Brockdorff N |
| Citation(s) |
30604745 |
| Submission date |
Oct 12, 2018 |
| Last update date |
Mar 19, 2019 |
| Contact name |
Michal R. Gdula |
| E-mail(s) |
michal.gdula@bioch.ox.ac.uk
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| Organization name |
Oxford University
|
| Street address |
South Parks Road
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| City |
Oxford |
| ZIP/Postal code |
OX1 3RF |
| Country |
United Kingdom |
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| Platforms (2) |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE115984 |
The non-canonical SMC protein SmcHD1 antagonises TAD formation on the inactive X chromosome |
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| Relations |
| BioProject |
PRJNA496037 |
| SRA |
SRP165596 |
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