|
| Status |
Public on Nov 02, 2018 |
| Title |
Loss of the FAT1 tumor suppressor promotes resistance to CDK4/6 inhibitors via the Hippo pathway |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Loss of FAT1 promotes resistance to CDK4/6 inhibitors. This study was to compare the differential mRNA expression of FAT1 crispr cells with parental cells, to identify the underlying mechanisms of resistance.
|
| |
|
| Overall design |
Examnination of differential RNA expression in FAT1 loss cells compared to MCF-7 parental cells.
|
| |
|
| Contributor(s) |
Chandarlapaty S, Li Q |
| Citation(s) |
30537512, 32907621 |
| Submission date |
Nov 01, 2018 |
| Last update date |
Sep 21, 2020 |
| Contact name |
Sarat CHANDARLAPATY |
| Organization name |
Memorial Sloan-Kettering Cancer Center
|
| Department |
HOPP
|
| Street address |
417 E 68th Street
|
| City |
NEW YORK |
| ZIP/Postal code |
10065 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA503479 |
| SRA |
SRP167647 |
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