|
| Status |
Public on Dec 26, 2019 |
| Title |
The affect of loss of Casz1 in C2C12 cells on super-enhancers |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
In the differereniated C2C12 cells, knockdown of Casz1 leads to a re-establishment of super-enhancers
|
| |
|
| Overall design |
C2C12 cells infected with control shRNA (shCtrl) or Casz1 shRNA (shCasz1) were induced to differentiate, then ChIP experiment was performed using anti-H3K27ac antibody and anti-H3K4me3 antibody.
|
| |
|
| Contributor(s) |
Liu Z, Zhang X, Thiele CJ |
| Citation(s) |
32060262 |
| Submission date |
Feb 06, 2019 |
| Last update date |
Mar 02, 2020 |
| Contact name |
Jack Shern |
| Organization name |
NCI
|
| Lab |
POB
|
| Street address |
10 Center drive
|
| City |
bethesda |
| State/province |
MD |
| ZIP/Postal code |
20892 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (6)
|
|
| This SubSeries is part of SuperSeries: |
| GSE126147 |
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation |
|
| Relations |
| BioProject |
PRJNA521145 |
| SRA |
SRP184207 |
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