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| Status |
Public on Jan 30, 2020 |
| Title |
Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Assessing intra-individual transcriptional heterogeneity in cALL patients using single cell RNA-seq
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| Overall design |
10X Genomics 3’ single cell RNA-seq: Pre-B t(12;21) [ETV6-RUNX1] acute lymphoblastic leukemia, Pre-B High hyper diploid [HHD] acute lymphoblastic leukemia, Pre-T acute lymphoblastic leukemia, Healthy pediatric bone marrow mononuclear cells. Annotations.tsv contains sample, cell cycle phase, tSNE/UMAP coordinates, and assigned cell type.
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| Contributor(s) |
Caron M, St-Onge P, Sontag T, Wang YC, Richer C, Ragoussis I, Sinnett D, Bourque G |
| Citation(s) |
32415257 |
| Submission date |
Jun 10, 2019 |
| Last update date |
Jun 11, 2021 |
| Contact name |
Guillaume Bourque |
| Organization name |
Mcgill university
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| Department |
Human Genetics
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| Street address |
740 Dr penfield
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| City |
Montreal |
| State/province |
QC |
| ZIP/Postal code |
H3A 0G1 |
| Country |
Canada |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (11)
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| Relations |
| BioProject |
PRJNA548203 |
| SRA |
SRP201012 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE132509_RAW.tar |
192.7 Mb |
(http)(custom) |
TAR (of MTX, TSV) |
| GSE132509_cell_annotations.tsv.gz |
3.2 Mb |
(ftp)(http) |
TSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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