|
| Status |
Public on Jun 29, 2020 |
| Title |
The BET inhibitor CPI203 promotes ex-vivo expansion of long-term repopulating human hematopoietic stem cells and megakaryocyte |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
RNA sequencing reveals the transcriptomic differences between cord blood cells expanded by CPI203/cytokines against DMSO/cytokines.
|
| |
|
| Overall design |
Cord blood CD133+ cells were expanded for 5 days in either CPI203/cytokines (B) or DMSO/cytokines (V) conditions. Each experiment starting from cell expansion was performed duplicately using cells from three different biological donors (a1-3).
|
| |
|
| Contributor(s) |
Hua P |
| Citation(s) |
32599615 |
| Submission date |
Nov 21, 2019 |
| Last update date |
Jul 15, 2020 |
| Contact name |
Peng Hua |
| E-mail(s) |
penghua@njmu.edu.cn
|
| Organization name |
Nanjing Medical University
|
| Department |
State Key Laboratory of Reproductive Medicine and Offspring Health
|
| Street address |
101 Longmiandadao
|
| City |
Nanjing |
| State/province |
Jiangsu |
| ZIP/Postal code |
211116 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA591011 |
| SRA |
SRP231175 |
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