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| Status |
Public on Sep 24, 2021 |
| Title |
Transcriptomic study of heart tissue from diabetic cardiomyopathy mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To explore the key genes involved in spontaneous diabetic cardiomyopathy, db/db and BKS mice were used to examine the differently expressed genes in the related progresses. Briely, the heart transcriptome of db/db and BKS mice was correlated with the heart function, cardiomyocyte ultrastructure and histopathology characters.
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| Overall design |
Two murine strains with C57BL/6 background were used in this study. Db/db group was used as the spontaneous diabetic cardiomyopathy group, and the BKS group was used as the healthy control group. Both groups of mice were housed under standard conditions with food and water provided without limitation and maintained on a 12 hour light/12 hour dark cycle. Body weight and food consumption were recorded every other day.
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| Contributor(s) |
Huang X, Su K |
| Citation(s) |
35242109 |
| Submission date |
Nov 20, 2020 |
| Last update date |
Mar 09, 2022 |
| Contact name |
Xin Huang |
| E-mail(s) |
xh@zju.edu.cn
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| Organization name |
Zhejiang University
|
| Street address |
88 Jiefang Road
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| City |
Hangzhou |
| State/province |
Zhejiang |
| ZIP/Postal code |
310009 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA679839 |
| SRA |
SRP293560 |
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