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Series GSE167360 Query DataSets for GSE167360
Status Public on Feb 24, 2021
Title RNA-seq of C3H/HeJ AA mice skin biopsies treated with JAK-selective inhibitors
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To define the molecular response to JAKi treatment, we performed RNA-seq analysis on a series of skin biopsies taken before and after systemic treatment with INCB039110 (JAK1i), CEP-33779 (JAK2i), PF-06651600 (JAK3i), ruxolitinib (JAK1/2i), tofacitinib (pan-JAKi) or vehicle control.
 
Overall design mRNA profiles to JAKi treatment of C3H/HeJ AA mice.
 
Contributor(s) Dai Z, Chen J, Chang Y
Citation(s) 33830087
Submission date Feb 23, 2021
Last update date May 25, 2021
Contact name Zhenpeng Dai
E-mail(s) zd2148@cumc.columbia.edu
Phone 2128514853
Organization name Columbia University
Department Dermatology
Street address 1150 St. Nicholas Ave
City New York
State/province NY
ZIP/Postal code 10025-2075
Country USA
 
Platforms (1)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (24)
GSM5102845 C3H/HeJ AA mice - Control pretreatment
GSM5102846 C3H/HeJ AA mice - JAK1i pretreatment
GSM5102847 C3H/HeJ AA mice - JAK2i pretreatment
Relations
BioProject PRJNA704387
SRA SRP307763

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE167360_processed_data-ALADIN_CTL_signature_genes-JAKi_AA-mice.xlsx 15.5 Kb (ftp)(http) XLSX
GSE167360_processed_data-Raw_gene_counts_JAKi_AA-mice.xlsx 3.6 Mb (ftp)(http) XLSX
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Raw data are available in SRA
Processed data are available on Series record
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