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| Status |
Public on Mar 05, 2010 |
| Title |
Expression data from Che-1 (AATF) depleted SKBR3 and MDA-468 cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Che-1 is a RNA Polymerase II binding protein involved in the regulation of gene transcription. We have observed that Che-1 depletion induces apoptosis in several cancer cells expressing mutated forms of p53. We used microarrays to investigate classes of genes regulated by Che-1 in one of these cell lines.
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| Overall design |
Total RNA was extracted from control and Che-1 depleted SKBR3 and MDA-468 cells 48 hours after transient transfection of siRNA.
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| Contributor(s) |
Bruno T, Benassi B |
| Citation(s) |
20708154 |
| Submission date |
Mar 04, 2010 |
| Last update date |
Jul 26, 2018 |
| Contact name |
maurizio fanciulli |
| E-mail(s) |
fanciulli@ifo.it
|
| Phone |
+390652662566
|
| Fax |
+390652662980
|
| Organization name |
regina elena cancer institute
|
| Department |
molecular medicine
|
| Lab |
epigenetics
|
| Street address |
via e chianesi 53
|
| City |
rome |
| ZIP/Postal code |
00144 |
| Country |
Italy |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
|
| Samples (10)
|
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| Relations |
| BioProject |
PRJNA124809 |
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