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| Status |
Public on Oct 20, 2022 |
| Title |
RNAseq analysis of brown adipose tissue (BAT) and thyroid of new-born lambs, subjected to short-term cold exposure, reveals signs of early whitening of BAT |
| Organism |
Ovis aries |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
An RNA-seq approach was utilized to characterise the transcriptome of brown adipose tissue and thyroid tissue in new-born Romney lambs after a short exposure (2 days) to cold conditions.
This study provides an in-depth expression network of the main characters involved in thermogenesis and fat whitening mechanisms that take place in the new-born lamb.
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| Overall design |
RNAseq of isolated RNA from brown adipose tissue and thyroid tissue of 15 new-born Romney lambs, exposed to cold (4°C, n=6) or ambient conditions (20-22°C, n=6) for two days. A control group was utilized as baseline for analysis (n=3), where tissues were collected at around 24 h after lambing.
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| Contributor(s) |
Graña-Baumgartner A, Dukkipati VR, Kenyon PR, Blair HT, López-Villalobos N, Biggs PJ |
| Citation(s) |
36295898 |
| Submission date |
Aug 01, 2022 |
| Last update date |
Oct 31, 2022 |
| Contact name |
Andrea Grana |
| E-mail(s) |
andrea.gbaum@gmail.com
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| Organization name |
Massey University
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| Street address |
Tennent Drive
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| City |
Palmerston North |
| ZIP/Postal code |
4472 |
| Country |
New Zealand |
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| Platforms (1) |
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| Samples (30)
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| GSM6426558 |
Thyroid, ambient, ID 233TA |
| GSM6426559 |
BAT, cold, ID 234FA |
| GSM6426560 |
Thyroid, cold, ID 234TA |
| GSM6426561 |
BAT, cold, ID 235FA |
| GSM6426562 |
Thyroid, cold, ID 235TA |
| GSM6426563 |
BAT, ambient, ID 236FA |
| GSM6426564 |
Thyroid, ambient, ID 236TA |
| GSM6426565 |
BAT, control, ID 237FA |
| GSM6426566 |
Thyroid, control, ID 237TA |
| GSM6426567 |
BAT, control, ID 238FA |
| GSM6426568 |
Thyroid, control, ID 238TA |
| GSM6426569 |
BAT, cold, ID 239FA |
| GSM6426570 |
Thyroid, cold, ID 239TA |
| GSM6426571 |
BAT, ambient, ID 240FA |
| GSM6426572 |
Thyroid, ambient, ID 240TA |
| GSM6426573 |
BAT, ambient, ID 241FA |
| GSM6426574 |
Thyroid, ambient, ID 241TA |
| GSM6426575 |
BAT, cold, ID 242FA |
| GSM6426576 |
Thyroid, cold, ID 242TA |
| GSM6426577 |
BAT, ambient, ID 243FA |
| GSM6426578 |
Thyroid, ambient, ID 243TA |
| GSM6426579 |
BAT, cold, ID 244FA |
| GSM6426580 |
Thyroid, cold, ID 244TA |
| GSM6426581 |
BAT, ambient, ID 245FA |
| GSM6426582 |
Thyroid, ambient, ID 245TA |
| GSM6426583 |
BAT, control, ID 246FA |
| GSM6426584 |
Thyroid, control, ID 246TA |
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| Relations |
| BioProject |
PRJNA864845 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE210259_Counts_RNAseq_lambs.txt.gz |
3.5 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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