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| Status |
Public on Jun 05, 2010 |
| Title |
Expression profiling of small intestine lamina propria dendritic cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Dendritic cells play a vital role in initiating robust immunity against pathogens as well as maintaining immunological tolerance to self antigens, food antigens and intestinal commensals. However, the intracellular signaling networks that program DCs to become tolerogenic are largely unknown. To address this, we analyzed gene expression profiles using microarray analysis of purified intestinal lamina propria DCs (CD11c+ CD11b+ DCs and CD11c+ CD11b- DCs) from mice.
Keywords: Lamina propria, DCs, cell type comparison
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| Overall design |
We sought to determine the expression profile of small intestine lamina propria CD11c+ cells. RNA was extracted from DCs sorted from mouse small intestine (CD11c+CD11b- and CD11c+CD11b+ cells) and hybridized on Affymetrix microarrays.
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| Contributor(s) |
Manicassamy S, Nakaya HI, Pulendran B |
| Citation(s) |
20705860 |
| Submission date |
Jun 03, 2010 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Helder I. Nakaya |
| E-mail(s) |
hnakaya@usp.br
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| Phone |
+551126481130
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| Organization name |
Universidade de São Paulo
|
| Lab |
csbiology.com
|
| Street address |
AVENIDA PROFESSOR LINEU PRESTES, 580, Block 17
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| City |
SÃO PAULO |
| State/province |
SÃO PAULO |
| ZIP/Postal code |
05508000 |
| Country |
Brazil |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (2) |
| GSM550401 |
Intestinal lamina propria CD11c+ CD11b- DCs |
| GSM550402 |
Intestinal lamina propria CD11c+ CD11b+ DCs |
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| This SubSeries is part of SuperSeries: |
| GSE22136 |
Comparison of splenic and small intestine lamina propria dendritic cells |
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| Relations |
| BioProject |
PRJNA129207 |
