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| Status |
Public on May 20, 2024 |
| Title |
Single-cell profiles of peripheral blood mononuclear cell (PBMC) and bone marrow mononuclear cell (BMMC) from pneumosepsis mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Immune disorder is a major pathological feature of sepsis, and its complex mechanisms have not been clarified so far. With the help of single-cell transcriptomics technology,we propose to explore the disregulated mechanisms of heterogeneous immune cells in the periphery and bone marrow of peumosepsis hosts.
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| Overall design |
PBMC and BMMC were isolated from klebsiella-pneumoniae-induced pneumosepsis mice at 0 hour (Control), 12 hours (KP1), 36 hours (KP2), and 90 hours (KP3), which represented four progressive status of the healthy, local pneumonia, distant spread, and ultimate sepsis, respectively.
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| Contributor(s) |
Long Q, Li J, Zheng Y, Gao Z |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Mar 26, 2024 |
| Last update date |
May 20, 2024 |
| Contact name |
Qiuyue Long |
| E-mail(s) |
longqiuyue@stu.xmu.edu.cn
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| Organization name |
Xiang’an Hospital of Xiamen University, School of Medicine, Xiamen University
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| Street address |
Xiang‘an east Road 2000
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| City |
Xiamen |
| State/province |
Fujian |
| ZIP/Postal code |
361104 |
| Country |
China |
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| Platforms (1) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA1092077 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE262512_RAW.tar |
1.1 Gb |
(http)(custom) |
TAR (of MTX, TSV) |
SRA Run Selector |
| Raw data are available in SRA |
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