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| Status |
Public on May 31, 2012 |
| Title |
Epigenetic regulation of miRNA in CLL [ChIP_hsa_miRNA_v2] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by genome tiling array
|
| Summary |
Genome-wide profiling of histone 3 lysine 4 trimethylation is used for identification of microRNA transcriptional start sites. Various cell types allow a broad range detection of putative promoters rather independent of tissue specific expression patterns. These data are used for identification of aberrant epigenetic regulation at the respective regions.
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| |
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| Overall design |
5 samples total: 1 primary CLL sample, 1 CLL related cell line -/+ 5-aza-2’-deoxycytidine (DAC) treatment (Granta-519), myeloid cell line Kasumi-1 (-/+ 5-aza-2’-deoxycytidine treatment); H3K4me3 enriched vs. Input
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| |
|
| Contributor(s) |
Baer C, Claus R |
| Citation(s) |
22710432 |
| |
| Submission date |
Oct 27, 2011 |
| Last update date |
Jan 17, 2013 |
| Contact name |
Constance Regina Baer |
| E-mail(s) |
c.baer@dkfz.de
|
| Organization name |
German Cancer Research Center
|
| Department |
Epigenomics and Cancer Risk Factors
|
| Lab |
Plass
|
| Street address |
Im Neuenheimer Feld 280
|
| City |
Heidelberg |
| ZIP/Postal code |
69120 |
| Country |
Germany |
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| Platforms (1) |
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| Samples (5)
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| This SubSeries is part of SuperSeries: |
| GSE33347 |
Epigenetic regulation of miRNA in CLL |
|
| Relations |
| BioProject |
PRJNA156645 |
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