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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Mar 05, 2014 |
| Title |
AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Gene-level expression profiles of 7 Aip knock-out (triplicates from each) and 9 Aip wild-type mouse embryonic fibroblast cell lines were studied using Affymetrix GeneChip Mouse Exon 1.0 ST Arrays
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| Overall design |
All samples were quantile-normalized by the RMA method (Robust Multichip Average) using re-mapped gene annotations from Brainarray Custom CDF files (MoEx10stv1, Version 14.1.0, http://brainarray.mbni.med.umich.edu/Brainarray/default.asp). A 2-way ANOVA was constructed to identify genes that differentially expressed between KO and WT samples. False discovery rate control (FDR) with Benjamini and Hochberg method was used to correct for multiple testing
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| Contributor(s) |
Tuominen I, Heliövaara E, Raitila A, Rautiainen M, Mehine M, Katainen R, Aittomäki V, Lehtonen HJ, Ahlsten M, Arola J, Hautaniemi S, Karhu A |
| Citation(s) |
24662816 |
| Submission date |
May 11, 2012 |
| Last update date |
Jun 05, 2014 |
| Contact name |
Miika Mehine |
| E-mail(s) |
miika.mehine@helsinki.fi
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| Organization name |
University of Helsinki
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| Street address |
P.O. Box 63 (Haartmaninkatu 8)
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| City |
Helsinki |
| ZIP/Postal code |
FI-00014 |
| Country |
Finland |
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| Platforms (1) |
| GPL15555 |
[MoEx-1_0-st] Affymetrix Mouse Exon 1.0 ST Array [CDF: Brainarray Ver. 14.1.0, MoEx10stv1_Mm_ENSG] |
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| Samples (30)
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| GSM930107 |
Mouse K642_4, replicate 2, AIP_KO |
| GSM930108 |
Mouse K680_2, AIP_wt |
| GSM930109 |
Mouse K680_6, replicate 2, AIP_KO |
| GSM930110 |
Mouse K680_6, replicate 1, AIP_KO |
| GSM930111 |
Mouse K680_6, replicate 3, AIP_KO |
| GSM930112 |
Mouse K728_6, replicate 1, AIP_KO |
| GSM930113 |
Mouse K728_6, replicate 2, AIP_KO |
| GSM930114 |
Mouse K728_6, replicate 3, AIP_KO |
| GSM930115 |
Mouse K728_8, replicate 1, AIP_KO |
| GSM930116 |
Mouse K728_8, replicate 2, AIP_KO |
| GSM930117 |
Mouse K728_8, replicate 3, AIP_KO |
| GSM930118 |
Mouse k349_4, AIP_wt |
| GSM930119 |
Mouse k349_5, replicate 1, AIP_KO |
| GSM930120 |
Mouse k349_5, replicate 2, AIP_KO |
| GSM930121 |
Mouse k349_5, replicate 3, AIP_KO |
| GSM930122 |
Mouse k349_8, replicate 1, AIP_KO |
| GSM930123 |
Mouse k349_8, replicate 2, AIP_KO |
| GSM930124 |
Mouse k349_8, replicate 3, AIP_KO |
| GSM930125 |
Mouse k358_2, AIP_wt |
| GSM930126 |
Mouse k358_6, replicate 1, AIP_KO |
| GSM930127 |
Mouse k358_6, replicate 2, AIP_KO |
| GSM930128 |
Mouse k358_6, replicate 3, AIP_KO |
| GSM930129 |
Mouse k367_2, AIP_wt |
| GSM930130 |
Mouse k370_5, AIP_wt |
| GSM930131 |
Mouse k401_5, AIP_wt |
| GSM930132 |
Mouse k431_6, AIP_wt |
| GSM930133 |
Mouse k564_1, AIP_wt |
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| Relations |
| BioProject |
PRJNA165687 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE37927_RAW.tar |
706.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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