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| Status |
Public on Jan 15, 2013 |
| Title |
Identification of Prognosis-Relevant Subgroups in Patients with Chemoresistant Triple Negative Breast Cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Triple-negative breast cancer (TNBC) patients with residual disease after neoadjuvant chemotherapy generally have worse outcome; however, some patients with residual tumor after neoadjuvant chemotherapy do not relapse. We hypothesize that there are subgroups of chemoresistant TNBC patients with different prognosis. In this study, 25 chemoresistant samples from 47 neoadjuvant chemotherapy-treated TNBC (The Methodist Hospital) are chosen for study
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| |
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| Overall design |
We used gene expression data of TNBC patients with residual disease and different prognosis to molecularly define the clinically relevant subgroups, and developed a 7-gene prognostic signature for chemoresistant TNBCs
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| |
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| Contributor(s) |
Chang JC |
| Citation(s) |
23549873 |
| Submission date |
Jan 15, 2013 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Keda Yu |
| E-mail(s) |
yukd@shca.org.cn
|
| Organization name |
The Methodist Hospital Cancer Center, Houston, Texas
|
| Street address |
6565 Fannin Street
|
| City |
Houston |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (25)
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| Relations |
| BioProject |
PRJNA186609 |
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