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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Apr 15, 2015 |
| Title |
Role of Capicua in metabolic system |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
CIC is a HMG box-containing transcriptional repressor evolutionarily conserved from C. elegans to human. It's known to associate with various types of cancer but physiological function of CIC remain largely unknown. In this study, we characterized Cic hypomorphic (Cic-L-/-) mice and identified critical roles for of CIC in drug metabolism and bile acid homeostasis.
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| Overall design |
Total RNA obtained from isolated liver tissue of Cic-L-/- mouse compared to liver tissue of normal mouse
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| Contributor(s) |
Kim E, Park S, Choi N, Lee J, Kim S, Yoe J, Jung H, Kim KT, Kang H, Fryer JD, Zoghbi HY, Hwang D, Lee Y |
| Citation(s) |
25653040 |
| Submission date |
Aug 13, 2014 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Jieon Lee |
| E-mail(s) |
wldjs1052@gmail.com
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| Organization name |
POSTECH
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| Department |
Chemical Engineering
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| Street address |
333. Techno Jungang-daero Hyeongpung-myeon, Dalseong-gun
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| City |
Daegue |
| ZIP/Postal code |
711-873 |
| Country |
South Korea |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA258134 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE60375_RAW.tar |
3.1 Mb |
(http)(custom) |
TAR |
| GSE60375_non-normalized.txt.gz |
1.3 Mb |
(ftp)(http) |
TXT |
| GSE60375_normalized.txt.gz |
751.8 Kb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
| Processed data are available on Series record |
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