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| Status |
Public on Jul 02, 2019 |
| Title |
Analysis of MACC1 dependent gene expression regulation in CRC cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We employed whole genome expression profiling to identify differential gene expression in the colorectal cancer (CRC) cell line SW480 (ATCC - CCL-228), dependent on the expression level of MACC1 (Metastasis Associated in Colon Cancer 1). SW480 cells with endogenously low expression levels of MACC1 were transfected either with CMV-promoter driven MACC1-cDNA or the empty vector, and selected for stable expression.
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| |
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| Overall design |
Total RNA of two biological replicates of both MACC1 overexpressing cells and vector control cells, respectively, was isolated and subjected to whole genome expression profiling.
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| Contributor(s) |
Schmid F, Wang Q |
| Citation(s) |
26686083 |
| Submission date |
Jul 01, 2015 |
| Last update date |
Jul 02, 2019 |
| Contact name |
Mathias Dahlmann |
| E-mail(s) |
mathias@kaddea.de
|
| Phone |
+49 30 9406 2389
|
| Organization name |
Charité University Medicine
|
| Department |
Experimental and Clinical Research Center
|
| Lab |
Translational Oncology of Solid Tumors
|
| Street address |
Robert-Rössle-Str. 10
|
| City |
Berlin |
| ZIP/Postal code |
13125 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL4133 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA288718 |
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