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| Status |
Public on Sep 01, 2020 |
| Title |
Expression data from C. elegans wdr-23 mutants |
| Organism |
Caenorhabditis elegans |
| Experiment type |
Expression profiling by array
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| Summary |
The WDR-23 protein regulates the transcription factor SKN-1 directly. C. elegans wdr-23 mutants have highly active SKN-1 and are stress resistant, long-lived, small, and reproduce poorly.
We used microarrays to measure global gene expression in wdr-23 mutants and to indentify genes regulated by SKN-1.
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| Overall design |
RNA extraction and hybridization on Affymetrix microarrays was performed on three genetic backgrounds at the L4 larval stage. The backgrounds were N2 (wildtype) with control RNAi, wdr-23(tm1817) mutants with skn-1 RNAi, and wdr-23(tm1817) mutants with control RNAi.
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| Contributor(s) |
Choe KP |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Sep 16, 2015 |
| Last update date |
Sep 02, 2020 |
| Contact name |
Keith Choe |
| E-mail(s) |
kchoe@ufl.edu
|
| Phone |
3522730139
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| Organization name |
University of Florida
|
| Street address |
876 Newell Dr, 321 Bartram Hall
|
| City |
Gainesville |
| State/province |
Florida |
| ZIP/Postal code |
32611 |
| Country |
USA |
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| Platforms (1) |
| GPL200 |
[Celegans] Affymetrix C. elegans Genome Array |
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| Samples (10)
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| GSM1886612 |
wdr-23 mutant skn-1 RNAi, biological rep1 |
| GSM1886613 |
wdr-23 mutant skn-1 RNAi, biological rep2 |
| GSM1886614 |
wdr-23 mutant skn-1 RNAi, biological rep3 |
| GSM1886615 |
wdr-23 mutant control RNAi, biological rep1 |
| GSM1886616 |
wdr-23 mutant control RNAi, biological rep2 |
| GSM1886617 |
wdr-23 mutant control RNAi, biological rep3 |
| GSM1886618 |
wdr-23 mutant control RNAi, biological rep4 |
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| Relations |
| BioProject |
PRJNA296035 |
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