|
| Status |
Public on Aug 12, 2016 |
| Title |
Comparative Methylome Analyses Reveal Human Brain Specific Methylated Regions Implicated in Transcription Regulation |
| Organism |
Macaca mulatta |
| Experiment type |
Methylation profiling by high throughput sequencing
|
| Summary |
To gain further insights into human brain specific epigenetic changes, we generated whole genome bisulfite sequencing methylation maps (methylomes) of rhesus macaque brains. These were then compared to methylomes of human and chimpanzee brains that were previously generated. We then performed validation experiments using targeted bisulfite sequencing.
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| |
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| Overall design |
Bisulfite-seq in prefrontal cortext of two male Macaca mulatta
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| |
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| Contributor(s) |
Mendizabal I, Yi SV |
| Citation(s) |
27563052 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 MH103517 |
Human Specific Brain DNA Methylation and Neuropsychiatric Diseases |
GEORGIA TECH RESEARCH CORPORATION |
TODD M PREUSS, YI |
|
| Submission date |
Jan 22, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Soojin V Yi |
| E-mail(s) |
soojinyi@gatech.edu
|
| Organization name |
Georgia Institute of Technology
|
| Department |
School of Biology
|
| Street address |
950 Atlantic Dr
|
| City |
Atlanta |
| State/province |
GA |
| ZIP/Postal code |
30318 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL14954 |
Illumina HiSeq 2000 (Macaca mulatta) |
|
| Samples (2) |
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| Relations |
| BioProject |
PRJNA309502 |
| SRA |
SRP068766 |
