|
| Status |
Public on Nov 15, 2007 |
| Title |
The Effect of Lifestyle on Gene Expression in Moroccan Amazighs |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The human transitions from nomadic to agrarian to urban lifestyles are likely to impact physiology and disease susceptibility. In order to estimate the magnitude of the impact of lifestyle on genome function, we profiled gene expression in total leukocytes of Moroccan Amazigh from three distinct localities. Despite great expression heterogeneity in humans, as much as one third of the PBMC transcriptome was found to differ between the localities.
Keywords: Population genomic comparison
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| |
|
| Overall design |
Total leukocytes were collected in December 2006 from three Moroccan Amazigh populations having three distinct lifestyles. Expression profiles of 10,173 transcripts were obtained for 46 individuals.
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| |
|
| Contributor(s) |
Idaghdour Y, Gibson GC, Story JD |
| Citation(s) |
18404217 |
| Submission date |
Aug 22, 2007 |
| Last update date |
Jan 18, 2013 |
| Contact name |
Youssef Idaghdour |
| E-mail(s) |
yidaghd@ncsu.edu
|
| Organization name |
NCSU
|
| Department |
Genetics
|
| Lab |
Gibson
|
| Street address |
South Gardner Hall
|
| City |
Raleigh |
| State/province |
NC |
| ZIP/Postal code |
27695 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL5764 |
Illumina Homo sapiens custom BeadChip |
|
| Samples (46)
|
|
| Relations |
| BioProject |
PRJNA102195 |
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