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    Zfp688 zinc finger protein 688 [ Mus musculus (house mouse) ]

    Gene ID: 69234, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Zfp688provided by MGI
    Official Full Name
    zinc finger protein 688provided by MGI
    Primary source
    MGI:MGI:1916484
    See related
    Ensembl:ENSMUSG00000045251 AllianceGenome:MGI:1916484
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810407K09Rik
    Summary
    Is expressed in several structures, including brain; genitourinary system; and retina nuclear layer. Orthologous to human ZNF688 (zinc finger protein 688). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 4.7), spleen adult (RPKM 4.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp688 in Genome Data Viewer
    Location:
    7 F3; 7 69.51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127018138..127023786, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127418963..127423241, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 764 Neighboring gene SMT3 suppressor of mif two 3 homolog 2, pseudogene 2 (S. cerevisiae) Neighboring gene myeloma-overexpressed gene 2 protein homolog Neighboring gene STARR-seq mESC enhancer starr_20181 Neighboring gene RIKEN cDNA B130055M24 gene Neighboring gene STARR-positive B cell enhancer ABC_E1095 Neighboring gene zinc finger protein 689 Neighboring gene STARR-seq mESC enhancer starr_20182 Neighboring gene STARR-seq mESC enhancer starr_20183 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134614302-134614485 Neighboring gene STARR-positive B cell enhancer ABC_E1742 Neighboring gene proline rich 14 Neighboring gene fibrosin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
    2. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
    3. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Tamplin OJ, et al. Dev Biol, 2011 Dec 15. PMID 22008794
    4. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article
    5. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC41678

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 688

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026999.4 → NP_081275.3  zinc finger protein 688

      Status: VALIDATED

      Source sequence(s)
      AI447502, BC038680, BQ550868, DV654233
      Consensus CDS
      CCDS21866.2
      UniProtKB/TrEMBL
      E9Q5M9
      Related
      ENSMUSP00000101907.2, ENSMUST00000106300.2
      Conserved Domains (6) summary
      smart00349
      Location:26 → 86
      KRAB; krueppel associated box
      COG5048
      Location:166 → 233
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:183 → 203
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:181 → 203
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:26 → 65
      KRAB; KRAB box
      pfam13465
      Location:196 → 220
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      127018138..127023786 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508179.5 → XP_006508242.1  zinc finger protein 688 isoform X1

      Conserved Domains (4) summary
      sd00017
      Location:145 → 165
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:143 → 165
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:25 → 66
      KRAB; KRAB box
      pfam13465
      Location:158 → 182
      zf-H2C2_2; Zinc-finger double domain

    2. XM_017312285.3 → XP_017167774.1  zinc finger protein 688 isoform X2

      UniProtKB/TrEMBL
      Q8K184
      Conserved Domains (3) summary
      sd00017
      Location:106 → 126
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:104 → 126
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:119 → 143
      zf-H2C2_2; Zinc-finger double domain

    3. XM_011241892.4 → XP_011240194.1  zinc finger protein 688 isoform X2

      UniProtKB/TrEMBL
      Q8K184
      Conserved Domains (3) summary
      sd00017
      Location:106 → 126
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:104 → 126
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:119 → 143
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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