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    Tuba3b tubulin, alpha 3B [ Mus musculus (house mouse) ]

    Gene ID: 22147, updated on 8-Feb-2024

    Summary

    Official Symbol
    Tuba3bprovided by MGI
    Official Full Name
    tubulin, alpha 3Bprovided by MGI
    Primary source
    MGI:MGI:1095408
    See related
    Ensembl:ENSMUSG00000067338 AllianceGenome:MGI:1095408
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    M[a]7; Tuba7
    Summary
    Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in keratoconus. Orthologous to human TUBA3D (tubulin alpha 3d). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 866.7) See more
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    Genomic context

    See Tuba3b in Genome Data Viewer
    Location:
    6 G3; 6 77.62 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (145561689..145567203)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (145615963..145621477)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene lamin tail domain containing 1 Neighboring gene predicted gene 15499 Neighboring gene predicted gene, 25373 Neighboring gene predicted gene 15704 Neighboring gene Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 Neighboring gene STARR-positive B cell enhancer mm9_chr6:145778656-145778957 Neighboring gene predicted gene, 38927

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    tubulin alpha-3 chain
    Names
    alpha-tubulin 3/7
    alpha-tubulin isotype M-alpha-3/7
    tubulin alpha-3/alpha-7 chain
    tubulin, alpha 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009449.3NP_033475.1  tubulin alpha-3 chain

      See identical proteins and their annotated locations for NP_033475.1

      Status: VALIDATED

      Source sequence(s)
      BC050769, BF152752, CK137160
      Consensus CDS
      CCDS39707.1
      UniProtKB/Swiss-Prot
      P05214
      UniProtKB/TrEMBL
      Q3TIZ0, Q5FW91
      Related
      ENSMUSP00000084713.7, ENSMUST00000087445.7
      Conserved Domains (1) summary
      PTZ00335
      Location:1440
      PTZ00335; tubulin alpha chain; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      145561689..145567203
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)