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    exoc3l2b exocyst complex component 3-like 2b [ Danio rerio (zebrafish) ]

    Gene ID: 565839, updated on 27-Mar-2024

    Summary

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    Official Symbol
    exoc3l2bprovided by ZNC
    Official Full Name
    exocyst complex component 3-like 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100728-5
    See related
    Ensembl:ENSDARG00000030782 AllianceGenome:ZFIN:ZDB-GENE-100728-5
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization and exocytosis. Predicted to be part of exocyst. Is expressed in hindbrain; neural crest; and pharyngeal arch. Orthologous to human EXOC3L2 (exocyst complex component 3 like 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See exoc3l2b in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (20139279..20200009, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (20203541..20264286, complement)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene activator of transcription and developmental regulator AUTS2 b Neighboring gene mediator complex subunit 13b Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14Ab Neighboring gene serine peptidase inhibitor, Kunitz type, 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Ovo1 links Wnt signaling with N-cadherin localization during neural crest migration. Piloto S, et al. Development, 2010 Jun. PMID 20463035, Free PMC Article
    2. A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis. Bielczyk-Maczyńska E, et al. PLoS Genet, 2014 Jul. PMID 25010335, Free PMC Article
    3. The Evolution of Duplicated Genes of the Cpi-17/Phi-1 (ppp1r14) Family of Protein Phosphatase 1 Inhibitors in Teleosts. Lang I, et al. Int J Mol Sci, 2020 Aug 9. PMID 32784920, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in exocyst localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of exocyst IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tumor necrosis factor alpha-induced protein 2
    Names
    exoc3l2
    sec6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      20139279..20200009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009291705.3 → XP_009289980.1  tumor necrosis factor alpha-induced protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M3B147
      Conserved Domains (1) summary
      cl19885
      Location:338 → 875
      Sec6; Exocyst complex component Sec6

    2. XM_689101.7 → XP_694193.4  tumor necrosis factor alpha-induced protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8N7TBH4, E7EY52, X1WGU0
      Related
      ENSDARP00000129449.1, ENSDART00000157149.2
      Conserved Domains (1) summary
      cl19885
      Location:282 → 819
      Sec6; Exocyst complex component Sec6

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394946.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      12382..73145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021472940.1 → XP_021328615.1  tumor necrosis factor alpha-induced protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q5H9
      Conserved Domains (1) summary
      cl19885
      Location:338 → 875
      Sec6; Exocyst complex component Sec6

    2. XM_021472941.1 → XP_021328616.1  tumor necrosis factor alpha-induced protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8N7TBH4, E7EY52, X1WGU0
      Conserved Domains (1) summary
      cl19885
      Location:282 → 819
      Sec6; Exocyst complex component Sec6
    Nucleotide Protein Strain
    Heading Accession and Version

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