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    nuak2 NUAK family, SNF1-like kinase, 2 [ Danio rerio (zebrafish) ]

    Gene ID: 560275, updated on 25-Apr-2024

    Summary

    Official Symbol
    nuak2provided by ZNC
    Official Full Name
    NUAK family, SNF1-like kinase, 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-563
    See related
    Ensembl:ENSDARG00000063661 AllianceGenome:ZFIN:ZDB-GENE-050208-563
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:rp71-11b17.3
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cellular response to glucose starvation; intracellular signal transduction; and protein phosphorylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human NUAK2 (NUAK family kinase 2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See nuak2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (508201..535454)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (470362..497731)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene cadherin, EGF LAG seven-pass G-type receptor 2 Neighboring gene dual serine/threonine and tyrosine protein kinase Neighboring gene cyclin D3 Neighboring gene mediator complex subunit 20 Neighboring gene bystin-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    NUAK family SNF1-like kinase 2
    XP_688764.3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      508201..535454
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_683672.9XP_688764.3  NUAK family SNF1-like kinase 2

      UniProtKB/TrEMBL
      A0A8N7TD19
      Related
      ENSDARP00000116197.1, ENSDART00000135403.2
      Conserved Domains (2) summary
      smart00220
      Location:29279
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14161
      Location:25279
      STKc_NUAK2; Catalytic domain of the Serine/Threonine Kinase, novel (nua) kinase family NUAK 2